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Catalog Number Size Price
LS-B16663-120 120 µl (0.6 mg/ml) $460 
ACTA2 / Smooth Muscle Actin Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTA2 / Smooth Muscle Actin Antibody - Human Prostate Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTA2 / Smooth Muscle Actin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTA2 / Smooth Muscle Actin Antibody - Western blot analysis of Mouse heart tissue, using ACTA2 Polyclonal Antibody at dilution of 1:500.
ACTA2 / Smooth Muscle Actin Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTA2 / Smooth Muscle Actin Antibody - Human Prostate Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTA2 / Smooth Muscle Actin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
ACTA2 / Smooth Muscle Actin Antibody - Western blot analysis of Mouse heart tissue, using ACTA2 Polyclonal Antibody at dilution of 1:500.
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PathPlus™ Polyclonal Rabbit anti‑Human ACTA2 / Smooth Muscle Actin Antibody (IHC, WB) LS‑B16663

PathPlus™ Polyclonal Rabbit anti‑Human ACTA2 / Smooth Muscle Actin Antibody (IHC, WB) LS‑B16663

Note: This antibody replaces LS-C402968
Antibody:
ACTA2 / Smooth Muscle Actin Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B16663-120
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ACTA2 / Smooth Muscle Actin Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
ACTA2 / Smooth Muscle Actin (SMA) belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. In immunohistochemistry, ACTA2 is to define smooth muscle cells and myofibroblasts in normal and malignant tissues. It is a common myoepithelial marker for normal and cancerous breast, salivary and sweat gland tissue. High levels of ACTA2 expression are correlated with aggressiveness, invasion and poorer prognosis in breast cancers positive for EGFR and ERBB2, basal cell carcinoma, and pancreatic ductal adenocarcinoma. ACTA2 can also be used to differentiate pleuropulmonary desmoid tumors (positive) from solitary fibrous tumors (negative). ACTA2 has membranous and cytoplasmic staining, and in normal tissue it is positive in smooth muscle cells, breast myoepithelial cells, chrondrocytes, decidual stromal cells, myofibroblasts, osteoblasts, pericytes, and salivary and sweat gland cells. References: Pancreas. 2010 Nov;39(8):1254-1262, PMID: 20467342; Oncotarget 2016 Jul; 8.31; 50570-50581, PMID: 28881584; Hum Pathol. 2010 Aug;41(8):1128-37, PMID: 20381122; Arch Pathol Lab Med 2006;130:1503, PMID: 17090192
Target
Human ACTA2 / Smooth Muscle Actin
Synonyms
ACTA2 | ACTVS | Alpha-actin-2 | Alpha-cardiac actin | AAT6 | Actin, aortic smooth muscle | ACTSA | Smooth Muscle Actin | MYMY5 | SMA
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Affinity purification
Modifications
Unmodified
Immunogen
Synthetic peptide of human ACTA2
Specificity
Human ACTA2 / Smooth Muscle Actin
Applications
  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:1000 - 1:5000)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.4, 0.05% Sodium Azide, 50% Glycerol
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ACTA2 / Smooth Muscle Actin
P62736 NM_001613 NP_001604.1

Validation

ACTA2 / Smooth Muscle Actin Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACTA2 / Smooth Muscle Actin Antibody - Human Prostate Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACTA2 / Smooth Muscle Actin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ ACTA2 / Smooth Muscle Actin Antibody for IHC, WB/Western, ELISA LS-B16663 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Angiogenic Potential of Human Adipose-Derived Mesenchymal Stromal Cells in Nanofibrillated Cellulose Hydrogel. Elle Koivunotko, Jasmi Snirvi, Arto Merivaara, Riina Harjumäki, Swarna Rautiainen, Minna Kelloniemi, Kirsi Kuismanen, Susanna Miettinen, Marjo Yliperttula, Raili Koivuniemi. Biomedicines. 2022 October;10:

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 2/26/2024