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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ACTA2 / Smooth Muscle Actin

actin, alpha 2, smooth muscle, aorta

ACTA2 / Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: actin, alpha 2, smooth muscle, aorta
Synonyms: ACTA2, ACTVS, Alpha-actin-2, Alpha-cardiac actin, AAT6, Actin, aortic smooth muscle, ACTSA, Smooth Muscle Actin, MYMY5, SMA
Target Sequences: NM_001613 NP_001604.1 P62736

Publications (3)

1
Infection of Human Retinal Pigment Epithelium with Chlamydia trachomatis. Boiko E, Maltsev D, Savicheva A, Shalepo K, Khusnutdinova T, Pozniak A, Kvetnoi I, Polyakova V, Suetov A. PloS one. 2015 10:e0141754. (IHC-P; Human) [Full Text Article] [PubMed:26536616] [PMC:PMC4633144]
2
Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response. Westendorp BF, Büller NVJA, Karpus ON, van Dop WA, Koster J, Versteeg R, Koelink PJ, Snel CY, Meisner S, Roelofs JJTH, Uhmann A, Ver Loren van Themaat E, Heijmans J, Hahn H, Muncan V, Wildenberg ME, van den Brink GR,. Cellular and molecular gastroenterology and hepatology. 2017 5:67-82. (WB; Human) [Full Text Article] [PubMed:29276753] Related Antibodies: LS-B3933.
3
Towards an in vitro fibrogenesis model of human vocal fold scarring. Graupp M, Rinner B, Frisch MT, Weiss G, Fuchs J, Sundl M, El-Heliebi A, Moser G, Kamolz LP, Karbiener M, Gugatschka M. European Archives of Oto-Rhino-Laryngology and Head & Neck. 2018 May;275:1211-1218. (Human) [Full Text Article] [PubMed:29520499] [PMC:PMC5893733] Related Antibodies: LS-B3933.

Filtered by: None
Target
ACTA2 / Smooth Muscle Actin (130)
Reactivity
Human (129)
Mouse (78)
Rat (85)
Baboon (5)
Bat (1)
Bovine (27)
Cat (1)
Chicken (31)
Dog (5)
Goat (1)
Guinea pig (3)
Hamster (2)
Horse (3)
Monkey (3)
Non-Human Primate (3)
Pig (19)
Rabbit (22)
Sheep (3)
Zebrafish (1)
Application
IHC (74)
IHC-Fr (14)
IHC-P (46)
WB (81)
Flo (18)
ELISA (21)
EM (1)
ICC (14)
IF (40)
IP (13)
Peptide-ELISA (1)
Host
rabbit (63)
mouse (66)
goat (1)
Isotype
IgG (32)
IgG,k (2)
IgG1 (7)
IgG1,k (2)
IgG2 (1)
IgG2a (14)
IgG2a,k (22)
Clonality
monoclonal mc (68)
polyclonal pc (62)
Clone
1A4 (11)
1A4 + ACTA2/791 (3)
1D11-2B9 (1)
1H8 (2)
2E2 (1)
4A4 (2)
4F4 (2)
6A12 (1)
ACTA2/791 (3)
ASM-1 (2)
AT132D3 (1)
BSB-15 (2)
IA4 (1)
SMAT2-1 (3)
SPM332 (2)
UMAB237 (2)
V24 (1)
Format
AMCA Conjugated (1)
AP Conjugated (1)
APC (3)
APC Conjugated (5)
Azide-free (6)
Biotin Conjugated (9)
Carrier-free (1)
Concentrated (1)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (6)
HiLyte Fluor 488 Conjugated (1)
HiLyte Fluor 555 Conjugated (1)
HiLyte Fluor 594 Conjugated (1)
HiLyte Fluor Conjugated (1)
HiLyte Plus 647 Conjugated (1)
HRP Conjugated (5)
PE Conjugated (5)
PerCP Conjugated (1)
Preservative Free (2)
Ready-to-Use (5)
TAMRA Conjugated (1)
Unconjugated (85)
Epitope
N-Terminus (30)
aa167-377 (8)
N-Terminal (1)
aa1-50 (1)
aa31-307 (1)
Publications
No (129)
Yes (1)
Showing 1-25 of 130 results

PathPlus™ ACTA2 / Smooth Muscle Actin Antibody (aa1-50) LS-B3933
Publications (2)
Publications (2)
Goat Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-ACTA2 antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Anti-ACTA2 antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody (clone 1A4) LS-B5147
Mouse Monoclonal [clone 1A4] (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IF, IHC, IHC-P
Unconjugated
250µl 0.04mg/ml  $505.00
Anti-Smooth Muscle Actin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:10.

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody LS-B7351
Mouse Monoclonal (IgG,k) to Human ACTA2 / Smooth Muscle Actin
Human
IHC, IHC-Fr, IHC-P
Unconjugated
50µl  $425.00
Anti-Smooth Muscle Actin antibody IHC of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody (N-Terminus) LS-B2506
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Human
IHC, IHC-P
Unconjugated
50µl 0.2mg/ml  $425.00
Anti-ACTA2 antibody IHC of human colon, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody LS-B4742
Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IHC, IHC-P
Unconjugated
250µl 0.2mg/ml  $515.00
Anti-Smooth Muscle Actin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Anti-Smooth Muscle Actin antibody IHC of human kidney, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

ACTA2 / Smooth Muscle Actin Antibody (clone 1A4, Biotin) LS-C87562
Mouse Monoclonal [clone 1A4] (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IF, IHC, IHC-P
Biotin Conjugated
100µl 200µg/ml  $335.00; 500µl 200µg/ml  $650.00; 1ml 200µg/ml  $875.00

ACTA2 / Smooth Muscle Actin Antibody (N-Terminus, Biotin) LS-C33052
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Mouse, Rat, Human
IHC, WB
Biotin Conjugated
50µg  $375.00

ACTA2 / Smooth Muscle Actin Antibody (N-Terminus, HiLyte Plus 647) LS-C33059
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Mouse, Rat, Human
IHC, WB
HiLyte Plus 647 Conjugated
50µg  $375.00

ACTA2 / Smooth Muscle Actin Antibody (clone 1A4, PE) LS-C124868
Mouse Monoclonal [clone 1A4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Rabbit, Mouse, Rat, Human
Flo
PE Conjugated
100tst 0.025mg/ml  $710.00

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody (clone 1H8) LS-B12102
Mouse Monoclonal [clone 1H8] (IgG1) to Human ACTA2 / Smooth Muscle Actin
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunofluorescence of NIH/3T3 cells using ACTA2 mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye.

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody (N-Terminus, Azide-free) LS-B2847
Mouse Monoclonal (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P
Unconjugated, Azide-free
50µg 1mg/ml  $485.00
Anti-ACTA2 antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.

ACTA2 / Smooth Muscle Actin Antibody (N-Terminus, clone 1A4) LS-C187560
Mouse Monoclonal [clone 1A4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Human
ELISA, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1mg  $325.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACTA2 / Smooth Muscle Actin Antibody LS-C402968
Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.5mg/ml  $205.00; 60µl 0.5mg/ml  $235.00; 120µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human prostate cancer using ACTA2 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of paraffin-embedded Human tonsil using ACTA2 Polyclonal Antibody at dilution of 1:30.

ACTA2 / Smooth Muscle Actin Antibody (N-Terminus, clone 1A4, Biotin) LS-C86744
Mouse Monoclonal [clone 1A4] (IgG2a) to Baboon ACTA2 / Smooth Muscle Actin
IF, IHC, IHC-Fr, IHC-P
Biotin Conjugated
20µg  $620.00

ACTA2 / Smooth Muscle Actin Antibody (N-Terminus, TAMRA) LS-C33054
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Mouse, Human
IHC, WB
TAMRA Conjugated
50µg  $365.00

ACTA2 / Smooth Muscle Actin Antibody (N-Terminus, FITC) LS-C182066
Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Human
IHC, WB
FITC Conjugated
50µg  $575.00

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody (clone 1D11-2B9) LS-B6000
Mouse Monoclonal [clone 1D11-2B9] (IgG1,k) to Human ACTA2 / Smooth Muscle Actin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg  $495.00
Anti-ACTA2 antibody IHC of human vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACTA2 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ACTA2 / Smooth Muscle Actin Antibody (clone 1A4, APC) LS-C182754
Mouse Monoclonal [clone 1A4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Human
Flo
APC Conjugated
100tst  $755.00

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody LS-B15365
Rabbit Monoclonal to Human ACTA2 / Smooth Muscle Actin
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)

ACTA2 / Smooth Muscle Actin Antibody (clone IA4) LS-C146642
Mouse Monoclonal [clone IA4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Chicken, Sheep, Mouse, Goat, Rat, Pig, Human
ELISA, EM, IHC, IHC-Fr, WB
Unconjugated
50µg 1mg/ml  $425.00
Frozen section of human small intestine immunostained with SM1 (1:1000)

ACTA2 / Smooth Muscle Actin Antibody LS-C416375
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µg  $305.00
Western blot of JK using alpha-SMA antibody ,The lane on the left is blocked with the antigen-specific peptide.

ACTA2 / Smooth Muscle Actin Antibody (clone 1A4, Azide-free) LS-C87563
Mouse Monoclonal [clone 1A4] (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IF, IHC, IHC-P
Unconjugated, Azide-free
100µl 1mg/ml  $545.00; 200µl 1mg/ml  $680.00
Formalin-fixed, paraffin-embedded human leiomyoma stained with peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of smooth muscle cells. This image was taken for the unmodified form of this product. Other forms have not been tested.

IHC-plus™ ACTA2 / Smooth Muscle Actin Antibody (N-Terminus) LS-B5211
Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IHC, IHC-P
Unconjugated
250µl  $425.00
Anti-ACTA2 antibody IHC of human lung, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

PathPlus™ ACTA2 / Smooth Muscle Actin Antibody (N-Terminus) LS-B1039
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Human
IHC, IHC-P
Unconjugated
100µg 0.2mg/ml  $425.00
Anti-ACTA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ACTA2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ACTA2 / Smooth Muscle Actin Antibody (N-Terminus) LS-C354532
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of Smooth Muscle Actin staining in human skeletal muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
Western blot analysis of Smooth Muscle Actin expression in MCF7 (A); K562 (B) whole cell lysates.
Showing 1-25 of 130 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).