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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
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866-206-6909 (Toll Free North America)
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ACTA2 / Smooth Muscle Actin

actin, alpha 2, smooth muscle, aorta

ACTA2 / Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: actin, alpha 2, smooth muscle, aorta
Synonyms: ACTA2, ACTVS, Alpha-actin-2, Alpha-cardiac actin, AAT6, Actin, aortic smooth muscle, ACTSA, Smooth Muscle Actin, MYMY5, SMA
Target Sequences: NM_001613 NP_001604.1 P62736

Publications (3)

1
Infection of Human Retinal Pigment Epithelium with Chlamydia trachomatis. Boiko E, Maltsev D, Savicheva A, Shalepo K, Khusnutdinova T, Pozniak A, Kvetnoi I, Polyakova V, Suetov A. PloS one. 2015 10:e0141754. (IHC-P; Human) [Full Text Article] [PubMed:26536616] [PMC:PMC4633144]
2
Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response. Westendorp BF, Büller NVJA, Karpus ON, van Dop WA, Koster J, Versteeg R, Koelink PJ, Snel CY, Meisner S, Roelofs JJTH, Uhmann A, Ver Loren van Themaat E, Heijmans J, Hahn H, Muncan V, Wildenberg ME, van den Brink GR,. Cellular and molecular gastroenterology and hepatology. 2017 5:67-82. (WB; Human) [Full Text Article] [PubMed:29276753] Related Antibodies: LS-B3933.
3
Towards an in vitro fibrogenesis model of human vocal fold scarring. Graupp M, Rinner B, Frisch MT, Weiss G, Fuchs J, Sundl M, El-Heliebi A, Moser G, Kamolz LP, Karbiener M, Gugatschka M. European Archives of Oto-Rhino-Laryngology and Head & Neck. 2018 May;275:1211-1218. (Human) [Full Text Article] [PubMed:29520499] [PMC:PMC5893733] Related Antibodies: LS-B3933.


ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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Cancer Pathology
Cancer
Goat Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Mouse Monoclonal [clone AT132D3] (IgG1,k) to Human ACTA2 / Smooth Muscle Actin
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
100µl   1mg/ml   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
120µl   0.6mg/ml   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Cancer Pathology
Cancer
Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Human
IHC, IHC-P
Unconjugated
50µg   0.2mg/ml   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Human Prostate, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Mouse Monoclonal to Human ACTA2 / Smooth Muscle Actin
Human
IHC-Fr, IHC-P
Unconjugated, Concentrated
0.1ml   $250.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-Smooth Muscle Actin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:10.
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Mouse Monoclonal [clone 1A4] (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IF, IHC, IHC-P
Unconjugated
250µl   0.04mg/ml   $505.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-Smooth Muscle Actin antibody IHC of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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Mouse Monoclonal (IgG,k) to Human ACTA2 / Smooth Muscle Actin
Human
IHC, IHC-Fr, IHC-P
Unconjugated
50µl   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human colon, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Human
IHC, IHC-P
Unconjugated
50µl   0.2mg/ml   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-Smooth Muscle Actin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IHC, IHC-P
Unconjugated
250µl   0.2mg/ml   $515.00
ACTA2 / Smooth Muscle Actin Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Mouse Monoclonal [clone 1H8] (IgG1) to Human ACTA2 / Smooth Muscle Actin
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P
Unconjugated, Azide-free
50µg   1mg/ml   $485.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Mouse Monoclonal [clone 1D11-2B9] (IgG1,k) to Human ACTA2 / Smooth Muscle Actin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $495.00
ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human lung, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IHC, IHC-P
Unconjugated
250µl   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Human Uterus, Myometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
Select
Mouse Monoclonal [clone 1A4] (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IF, IHC, IHC-P
Biotin Conjugated
100µl   200µg/ml   $335.00; 500µl   200µg/ml   $650.00; 1ml   200µg/ml   $875.00
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Mouse Monoclonal [clone 1A4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Rabbit, Mouse, Rat, Human
Flo
PE Conjugated
100tst   0.025mg/ml   $710.00
ACTA2 / Smooth Muscle Actin Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Mouse Monoclonal [clone 1A4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Human
ELISA, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1mg   1mg/ml   $325.00
Select
Mouse Monoclonal [clone 1A4] (IgG2a) to Baboon ACTA2 / Smooth Muscle Actin
IF, IHC, IHC-Fr, IHC-P
Biotin Conjugated
20µg   40µg/ml   $575.00
ACTA2 / Smooth Muscle Actin Antibody - Immunohistochemical analysis of Smooth Muscle Actin staining in human skeletal muscle formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX. w
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Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
Select
Rabbit Polyclonal (IgG) to Human ACTA2 / Smooth Muscle Actin
Human
IHC, WB
FITC Conjugated
50µg   $575.00
Select
Mouse Monoclonal [clone 1A4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Human
Flo
APC Conjugated
100tst   $770.00
ACTA2 / Smooth Muscle Actin Antibody - Frozen section of human small intestine immunostained with SM1 (1:1000)
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Mouse Monoclonal [clone IA4] (IgG2a) to Human ACTA2 / Smooth Muscle Actin
Chicken, Sheep, Mouse, Goat, Rat, Pig, Human
ELISA, EM, IHC, IHC-Fr, WB
Unconjugated
50µg   1mg/ml   $425.00
ACTA2 / Smooth Muscle Actin Antibody - Formalin-fixed, paraffin-embedded human leiomyoma stained with peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of smooth muscle cells. This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 1A4] (IgG2a,k) to Human ACTA2 / Smooth Muscle Actin
Chicken, Bovine, Rabbit, Mouse, Rat, Baboon, Human
IF, IHC, IHC-P
Unconjugated, Azide-free
100µl   1mg/ml   $545.00; 200µl   1mg/ml   $680.00
ACTA2 / Smooth Muscle Actin Antibody - Western blot of JK using alpha-SMA antibody ,The lane on the left is blocked with the antigen-specific peptide.
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Rabbit Polyclonal to Human ACTA2 / Smooth Muscle Actin
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µg   50µl   1mg/ml   $255.00; 100µg   100µl   1mg/ml   $305.00
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).