LSBio offers a wide range of products useful for differentiating the stages of apoptosis in histology
and morphological analysis. Elisa kits, antibodies, proteins, biochemicals and assay kits are available
to important targets in each of the major categories of apoptosis.
Apoptosis, or programmed cell death, is an organized process the body uses to eliminate senescent
and unnecessary cells. This process is important for normal embryologic development, endometrial cycling,
and post-partum uterine myometrial regression. Apoptosis is controlled by a variety of triggers,
including heat, toxins, radiation, and viral infection. Molecular factors can also induce or inhibit
apoptosis, and are frequently abnormally expressed in cancers. For example, high expression of the
anti-apoptotic factor BCL2
in follicular lymphomas leads to immortalization and unchecked proliferation of
malignant cells. Targeting such factors is an area of active interest for cancer treatment.