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PathPlusTM ACTA2 / Smooth Muscle Actin Antibodies
ACTA2 / Smooth Muscle Actin (SMA) belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. In immunohistochemistry, ACTA2 is to define smooth muscle cells and myofibroblasts in normal and malignant tissues. It is a common myoepithelial marker for normal and cancerous breast, salivary and sweat gland tissue. High levels of ACTA2 expression are correlated with aggressiveness, invasion and poorer prognosis in breast cancers positive for EGFR and ERBB2, basal cell carcinoma, and pancreatic ductal adenocarcinoma. ACTA2 can also be used to differentiate pleuropulmonary desmoid tumors (positive) from solitary fibrous tumors (negative). ACTA2 has membranous and cytoplasmic staining, and in normal tissue it is positive in smooth muscle cells, breast myoepithelial cells, chrondrocytes, decidual stromal cells, myofibroblasts, osteoblasts, pericytes, and salivary and sweat gland cells. References: Pancreas. 2010 Nov;39(8):1254-1262, PMID: 20467342; Oncotarget 2016 Jul; 8.31; 50570-50581, PMID: 28881584; Hum Pathol. 2010 Aug;41(8):1128-37, PMID: 20381122; Arch Pathol Lab Med 2006;130:1503, PMID: 17090192

5 PathPlusTM Antibodies
☰ Filters
Antibodies (5)
Primary (5)
ACTA2 / Smooth Muscle Actin (5)
Human (5)
Mouse (2)
Rat (2)
Bat (1)
Bovine (1)
Chicken (1)
Dog (1)
Hamster (1)
Horse (1)
Monkey (1)
Pig (1)
Rabbit (1)
IHC (2)
IHC-Fr (1)
IHC-P (5)
WB (3)
ELISA (2)
ICC (1)
IF (1)
Peptide-ELISA (1)
rabbit (2)
mouse (2)
goat (1)
Product Group
PathPlus Cancer (5)
PathPlus Cancer Pathology (5)
IgG (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (3)
AT132D3 (1)
Concentrated (1)
Unconjugated (5)
N-Terminus (1)
aa1-50 (1)
No (4)
Yes (1)
ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human colon, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Select
Cancer Pathology
Cancer
ACTA2 / Smooth Muscle Actin Goat anti-Human Polyclonal (aa1-50) Antibody
Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$440
ACTA2 / Smooth Muscle Actin Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
ACTA2 / Smooth Muscle Actin Mouse anti-Human Monoclonal (AT132D3) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
100 µl/$460
ACTA2 / Smooth Muscle Actin Antibody - Human Prostate, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
ACTA2 / Smooth Muscle Actin Mouse anti-Human Monoclonal (Concentrated) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Concentrated
0.05 ml/$460
ACTA2 / Smooth Muscle Actin Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
ACTA2 / Smooth Muscle Actin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
120 µl/$460
ACTA2 / Smooth Muscle Actin Antibody - Anti-ACTA2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer Pathology
Cancer
ACTA2 / Smooth Muscle Actin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Viewing 1-5 of 5 product results