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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCL4 / MIP‑1 Beta Antibody (aa22‑48, AP) LS‑C502591
MIP-1 Beta antibody LS-C502591 is an AP-conjugated rabbit polyclonal antibody to MIP-1 Beta (CCL4) from human and mouse. Validated for ELISA, IHC and WB.
Antibody
Catalog
Size
Price
LS-C502591-200
200 µl
$680

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Antibody
Species:
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

MIP-1 Beta antibody LS-C502591 is an AP-conjugated rabbit polyclonal antibody to MIP-1 Beta (CCL4) from human and mouse. Validated for ELISA, IHC and WB.

Specifications

Target
Human CCL4 / MIP-1 Beta
Synonyms
CCL4, ACT2, Act-2, AT744.1, C-C motif chemokine 4, Chemokine (C-C motif) ligand 4, CC chemokine ligand 4, HC21, LAG1, MIP1B, MIP1B1, LAG-1, SCYA2, Secreted protein G-26, SIS-gamma, MIP-1-beta, MIP-1-beta(1-69), Small-inducible cytokine A4, T-cell activation protein 2, G-26, Lymphocyte-activation gene 1, PAT 744, Protein H400, SCYA4
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Alkaline Phosphatase. Also available Unconjugated or conjugated with FITC, PE, APC, Biotin, HRP.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Epitope
aa22-48
Specificity
This CCL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-48 amino acids from the Central region of human CCL4.
Presentation
PBS, pH 7.2, No preservatives added
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
About CCL4 / MIP-1 Beta
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. P13236 NM_002984 NP_002975.1


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Requested From: United States
Date Requested: 11/16/2018

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