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IL1A / IL-1 Alpha

interleukin 1, alpha

IL1A / IL-1 Alpha is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Gene Name: interleukin 1, alpha
Family/Subfamily: IL-1 , not assigned-IL-1
Synonyms: IL1A, Hematopoietin-1, IL-1 alpha, IL1, IL1-ALPHA, IL1 Alpha, Interleukin-1 alpha, IL-1A, IL1F1, Pro-interleukin-1-alpha, Preinterleukin 1 alpha, Interleukin 1, alpha
Target Sequences: NM_000575 NP_000566.3 P01583

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Products
Antibodies (264)
Primary (264)
IL1A / IL-1 Alpha (264)
Human (115)
Mouse (37)
Rat (43)
Bovine (3)
Chimpanzee (3)
Dog (19)
Gibbon (3)
Goat (19)
Guinea pig (8)
Horse (32)
Monkey (3)
Monkey-Rhesus (4)
Pig (8)
Rabbit (10)
Sheep (3)
IHC (30)
IHC-Fr (1)
IHC-P (7)
WB (232)
Flo (7)
ELISA (68)
ICC (2)
IF (14)
IP (1)
Neut (10)
Peptide-ELISA (2)
rabbit (160)
mouse (90)
goat (4)
guinea pig (8)
hamster (2)
Product Group
Coronavirus Antibodies Proteins cDNAs (261)
Cytokine Release Syndrome (263)
Cytokine Release Syndrome Antibodies (261)
IHCPlus (1)
IgG (70)
IgG1 (20)
IgG1,k (5)
IgG2a (4)
IgG2a,k (8)
IgG2b (1)
IgG2b,k (24)
monoclonal mc (93)
polyclonal pc (171)
148 (1)
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74 (1)
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aa113-271 (12)
aa101-270 (8)
aa111-204 (8)
aa116-270 (8)
aa132-265 (8)
aa132-267 (8)
aa90-268 (8)
aa94-262 (8)
aa95-269 (8)
aa98-266 (8)
aa98-271 (8)
aa177-206 (7)
aa65-94 (7)
aa38-87 (4)
N-Terminal (1)
Phe8 (1)
aa1-112 (1)
aa8-57 (1)
No (264)
IL1A / IL-1 Alpha Antibody - Anti-IL1 Alpha antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:400.
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (3A6F11) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL1A / IL-1 Alpha Antibody - IHC of paraffin-embedded Human breast tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (OTI2F8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
IL1A / IL-1 Alpha Antibody - IHC of paraffin-embedded Human breast tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (Carrier-free) (OTI2F8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IL1A / IL-1 Alpha Antibody - Western Blot (non-reducing) of IL1A / IL1 Alpha antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1A / IL-1 Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL1A / IL-1 Alpha Antibody - Western Blot (non-reducing) of IL1A / IL1 Alpha antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1A / IL-1 Alpha Goat anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL1A / IL-1 Alpha Antibody - Western Blot (non-reducing) of IL1A / IL1 Alpha antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1A / IL-1 Alpha Goat anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (aa1-112) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$896
IL1A / IL-1 Alpha Antibody
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$445
IL1A / IL-1 Alpha Antibody - Western blot of recombinant IL1A / IL1 Alpha.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL1A / IL-1 Alpha Rabbit anti-Guinea pig Polyclonal (aa111-204) Antibody
Guinea pig
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
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IL1A / IL-1 Alpha Goat anti-Rabbit Polyclonal Antibody
Rabbit
ELISA
Unconjugated
0.1 mg/$596
IL1A / IL-1 Alpha Antibody - IHC of IL-1 (F8) pAb in paraffin-embedded human lung carcinoma tissue.
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IL1A / IL-1 Alpha Rabbit anti-Human Polyclonal (Phe8) Antibody
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
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IL1A / IL-1 Alpha Mouse anti-Mouse Monoclonal (Preservative Free) (Flo1) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
0.1 mg/$570
IL1A / IL-1 Alpha Antibody - IHC of paraffin-embedded Human liver tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (OTI3C3) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$419
IL1A / IL-1 Alpha Antibody - IHC of paraffin-embedded Human liver tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (Carrier-free) (OTI3C3) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$483
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IL1A / IL-1 Alpha Rabbit anti-Mouse Monoclonal (Preservative Free) (148) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
IL1A / IL-1 Alpha Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (OTI2F11) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
IL1A / IL-1 Alpha Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-IL1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (Carrier-free) (OTI2F11) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IL1A / IL-1 Alpha Antibody - Immunochemical staining of mouse IL1A in mouse liver with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
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IL1A / IL-1 Alpha Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
IHC-P
Unconjugated, Preservative Free
50 µl/$317; 100 µl/$375; 200 µl/$473
IL1A / IL-1 Alpha Antibody - Western Blot; Sample: Recombinant protein.
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IL1A / IL-1 Alpha Mouse anti-Human Monoclonal (HRP) Antibody
Rat, Human
WB
HRP Conjugated
100 µl/$333; 200 µl/$385; 500 µl/$560; 1 ml/$672; 2 ml/$909; 5 ml/$1,529
IL1A / IL-1 Alpha Antibody - Western blot of IL1A / IL-1 Alpha antibody.
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IL1A / IL-1 Alpha Rabbit anti-Dog Polyclonal (aa94-262) Antibody
Dog
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
IL1A / IL-1 Alpha Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with IL1A Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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IL1A / IL-1 Alpha Rabbit anti-Human Polyclonal (aa177-206) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
IL1A / IL-1 Alpha Antibody - Western Blot of Rabbit Anti-Human IL-1 alpha Antibody. Lane 1: Opal Prestained Molecular Weight Ladder  Lane 2: IL-1 alpha 50ng. Lane 3: MEF WC lysate 10ng. Lane 4: MEF LPS stimulated 10ng.BlockOut Buffer for 30min at RT. Primary Antibody: Anti-IL-1a 1µg/mL overnight at 4°C. Secondary Antibody: Goat anti-Rabbit HRP at 1:70, 000) for 30min at RT.
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IL1A / IL-1 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, Neut, WB
Unconjugated
1 mg/$1,225
IL1A / IL-1 Alpha Antibody - Western Blot; Sample: Recombinant IL1a, Rabbit.
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IL1A / IL-1 Alpha Guinea pig anti-Rabbit Polyclonal (aa132-267) Antibody
Rabbit
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL1A / IL-1 Alpha Antibody - Western Blot of rabbit Anti-Human IL-1 alpha Antibody. Lane 1: Opal Prestained Molecular Weight Ladder Lane 2: IL-1 alpha 50ng. Lane 3: MEF WC lysate 10ng. Lane 4: MEF LPS stimulated 10ng. Blocking: BlockOut Buffer for 30min at RT. Primary Antibody: Anti-IL-1a 1µg/mL overnight at 4°C. Secondary Antibody: Goat anti-Rabbit HRP at 1:70, 000) for 30min at RT.
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IL1A / IL-1 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, Neut, WB
Unconjugated
100 µl/$567
IL1A / IL-1 Alpha Antibody - Western Blot of rabbit Anti-Human IL-1 alpha Antibody. Lane 1: Opal Prestained Molecular Weight Ladder Lane 2: IL-1 alpha 50ng. Lane 3: MEF WC lysate 10ng. Lane 4: MEF LPS stimulated 10ng. Blocking: BlockOut Buffer for 30min at RT. Primary Antibody: Anti-IL-1a 1µg/mL overnight at 4°C. Secondary Antibody: Goat anti-Rabbit HRP at 1:70, 000) for 30min at RT.
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IL1A / IL-1 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, Neut, WB
Unconjugated
25 µl/$304
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).