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Anti-p66 / SHC Antibody (phospho-Tyr427) LS-C124525

Ordering

Wt. Vol. Conc. Price
50 µg - - $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular p66 / SHC Antibodies

Anti-p66 / SHC Antibody (clone 3F4) IHC-plus™ LS-B4416
Mouse Monoclonal [clone 3F4] (IgG,k) to Human p66 / SHC
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA, Proximity Ligation Assay
Unconjugated
Immunohistochemistry Image
Anti-p66 / SHC Antibody (phospho-Tyr427) LS-C34237
Rabbit Polyclonal (IgG) to Human p66 / SHC
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-p66 / SHC Antibody (phospho-Ser36, clone 6E10) LS-C10125
Mouse Monoclonal [clone 6E10] (IgG1) to Human p66 / SHC
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig
Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human p66 / SHC
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig, Xenopus, Zebrafish
IHC, Western blot
Unconjugated

Details

Human p66 / SHC
Rabbit
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig, Xenopus, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)

Specificity and Use

p66 / SHC antibody was raised against synthetic phosphopeptide corresponding to human Shc1 around the phosphorylation site of tyrosine 427 (P-S-YP-V-N).
pTyr427
Recognizes human Shc1 when phosphorylated at (Tyr427). Species cross-Reactivity: mouse, rat.
Suitable for use in Western Blot, and Immunohistochemistry. Western Blot:1:500-1:1000. Immunohistochemistry:1:50-1:100.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months.
For research use only.

About p66 / SHC

P29353 NM_003029 NP_003020.2

SHC1 Antibody, p46 shc Antibody, p52 shc Antibody, SH2 domain protein C1 Antibody, p66 Antibody, SHCA Antibody, SHC Antibody, SHC-transforming protein 1 Antibody, SHC-transforming protein 3 Antibody, SHC-transforming protein A Antibody

Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.

Requested From: United States
Date Requested: 12/11/2016

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