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Anti-p66 / SHC Antibody (phospho-Tyr317) LS-C10115


Wt. Vol. Conc. Price
- 100 µl - $485
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular p66 / SHC Antibodies

Anti-p66 / SHC Antibody (phospho-Ser36, clone 6E10) LS-C10125
Mouse Monoclonal [clone 6E10] (IgG1) to Human p66 / SHC
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig
Western blot, ELISA
Anti-p66 / SHC Antibody (phospho-Tyr427) LS-C34237
Rabbit Polyclonal (IgG) to Human p66 / SHC
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot
Immunohistochemistry Image
Anti-p66 / SHC Antibody (clone 3F4) IHC-plus™ LS-B4416
Mouse Monoclonal [clone 3F4] (IgG,k) to Human p66 / SHC
IHC - Paraffin, Immunofluorescence, Western blot, ELISA, Proximity Ligation Assay
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human p66 / SHC
Human, Mouse, Rat
Western blot


Human p66 / SHC
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein A purified


Western blot (1:1000)

Specificity and Use

p66 / SHC antibody was raised against synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Tyr317 of human Shc.
Detects human Shc only when phosphorylated at tyrosine 317. Species cross-reactivity: Mouse and rat.
Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4?C with gentle shaking, overnight.


10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol. No preservative added.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About p66 / SHC

P29353 NM_003029 NP_003020.2

SHC1 Antibody, p46 shc Antibody, p52 shc Antibody, SH2 domain protein C1 Antibody, p66 Antibody, SHCA Antibody, SHC Antibody, SHC-transforming protein 1 Antibody, SHC-transforming protein 3 Antibody, SHC-transforming protein A Antibody

Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.

Requested From: United States
Date Requested: 10/27/2016

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