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Anti-MCL1 / MCL 1 Antibody IHC-plus™ LS-B3686

Note: This antibody replaces LS-C63135

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MCL1 / MCL 1 Antibodies

Anti-MCL1 / MCL 1 Antibody (FITC) LS-C262847
Rabbit Polyclonal (IgG) to Human MCL1 / MCL 1
Human, Mouse
IHC, Western blot, Flow Cytometry, ELISA
FITC Conjugated
Anti-MCL1 / MCL 1 Antibody (clone 2E11) IHC-plus™ LS-B10210
Mouse Monoclonal [clone 2E11] (IgG2a) to Human MCL1 / MCL 1
Human
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MCL1 / MCL 1
Human, Monkey, Dog, Guinea pig, Pig, Rabbit
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated

Details

Human MCL1 / MCL 1
Rabbit
Human, Monkey, Dog, Guinea pig, Pig, Rabbit (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence
  • Western blot

Specificity and Use

MCL1 / MCL 1 antibody was raised against synthetic peptide derived from the sequence of human Mcl-1, conjugated to KLH.
Immunohistochemistry: LS-B3686 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3686 was determined to be 10 ug/ml.

Packaging

PBS, 0.09% sodium azide
Store at -20°C.
For research use only.

About MCL1 / MCL 1

Q07820 NM_021960 NP_068779.1

MCL1 Antibody, BCL2L3 Antibody, Bcl-2-like protein 3 Antibody, Bcl-2-related protein EAT/mcl1 Antibody, Bcl2-L-3 Antibody, MCL1S Antibody, MCL1L Antibody, Myeloid cell leukemia ES Antibody, MCL 1 Antibody, MCL1-ES Antibody, TM Antibody, EAT Antibody, Mcl-1 Antibody

Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types.

Immunohistochemistry

Immunohistochemistry
Anti-MCL1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3686 concentration 10 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-MCL1 antibody IHC of human small intestine, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3686 concentration 10 ug/ml.

Immunofluorescence

Immunofluorescence
Confocal immunofluorescent staining of HeLa cells using Mcl-1 polyclonal antibody (green); nuclei are stained in blue pseudocolor using DRAQ5.

Western blot

Western blot
Western blot of human epidermoid carcinoma A431 cell lysate, probed with Mcl-1 polyclonal antibody.

Requested From: United States
Date Requested: 12/11/2016

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