LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
MCL1 / MCL 1 Antibody (aa121‑139) LS‑C8943
MCL 1 antibody LS-C8943 is an unconjugated rabbit polyclonal antibody to MCL 1 (MCL1) from human, dog, guinea pig and other species. Validated for WB.
Antibody
Catalog
Size
Price
LS-C8943-25
25 µg
$345
LS-C8943-100
100 µg
$395

Popular MCL1 / MCL 1 Products

Anti-MCL1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B586 concentration 2 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Western blot
IHC of paraffin-embedded human lymph node showing cytoplasmic localization using MCL-1 antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Anti-MCL1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5215 dilution 1:25.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, Flow Cytometry, ELISA
Anti-MCL1 / MCL 1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10210 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry

Product Description

MCL 1 antibody LS-C8943 is an unconjugated rabbit polyclonal antibody to MCL 1 (MCL1) from human, dog, guinea pig and other species. Validated for WB.
About MCL1 / MCL 1
Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Q07820 NM_021960 NP_068779.1

MCL1 Antibody, BCL2L3 Antibody, Bcl-2-like protein 3 Antibody, Bcl-2-related protein EAT/mcl1 Antibody, Bcl2-L-3 Antibody, MCL1S Antibody, MCL1L Antibody, Myeloid cell leukemia ES Antibody, MCL 1 Antibody, MCL1-ES Antibody, TM Antibody, EAT Antibody, Mcl-1 Antibody


Specifications

Target
Human MCL1 / MCL 1
Host
Rabbit
Reactivity
Human, Monkey, Dog, Guinea pig, Pig, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
MCL1 / MCL 1 antibody was raised against human Mcl-1 synthetic peptide (amino acid residues 121-139), conjugated to KLH.
Epitope
aa121-139
Specificity
This immunoaffinity purified antibody Detects a ~42/43kD protein doublet, corresponding to the expected molecular mass of Mcl-1 on SDS-PAGE immunoblots, in samples from human, canine, guinea pig, monkey, porcine and rabbit. The antibody specificity is confirmed by peptide inhibition studies. An additional protein at ~33kD may also be detected. Other additional proteins may also be seen in some samples.
Usage
Western Blot (ECL): 0.1 ug/mL. Positive control: HeLa Heat Shocked Cell Lysate.
Presentation
25 mM Sodium Borate, BBS, pH 8.2, 75 mM NaCl 5 mM EDTA, 100 mM Boric acid
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Requested From: United States
Date Requested: 8/14/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number