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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CLU / Clusterin Antibody (aa227‑447, Biotin) LS‑C298373
Clusterin antibody LS-C298373 is a biotin-conjugated rabbit polyclonal antibody to Clusterin (CLU) from mouse and rat. Validated for IHC and WB.
Catalog
Size
Price
LS-C298373-100
100 µl (0.5 mg/ml)
$435

Popular CLU / Clusterin Products

Antibody
Species: Human
Applications: IHC, IHC - Frozen, Western blot, Flow Cytometry, ELISA
Antibody (0.3 ug/ml) staining of Rat Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
Species: Mouse, Rat
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-Clusterin antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2852 concentration 5 ug/ml.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: ELISA

Product Description

Clusterin antibody LS-C298373 is a biotin-conjugated rabbit polyclonal antibody to Clusterin (CLU) from mouse and rat. Validated for IHC and WB.
About CLU / Clusterin
Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. P10909 NM_001831 NP_001822.3

CLU Antibody, APO-J Antibody, Apolipoprotein J Antibody, CLU1 Antibody, Clusterin Antibody, Complement lysis inhibitor Antibody, CLI Antibody, AAG4 Antibody, Aging-associated protein 4 Antibody, Ku70-binding protein 1 Antibody, KUB1 Antibody, SGP2 Antibody, APOJ Antibody, SGP-2 Antibody, Sulfated glycoprotein 2 Antibody, CLU2 Antibody, Complement cytolysis inhibitor Antibody, NA1/NA2 Antibody, SP-40 Antibody


Specifications

Target
Rat CLU / Clusterin
Host
Rabbit
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC.
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1:100 - 1:400)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CLU / Clusterin antibody was raised against recombinant CLU (Ser227-Glu447) expressed in E. coli.
Epitope
aa227-447
Specificity
The antibody is a rabbit polyclonal antibody raised against CLU. It has been selected for its ability to recognize CLU in immunohistochemical staining and western blotting.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

Western blot of recombinant CLU / Clusterin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CLU / Clusterin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant CLU / Clusterin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CLU / Clusterin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant CLU / Clusterin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CLU / Clusterin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of recombinant CLU / Clusterin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant CLU / Clusterin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 7/21/2018

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