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Anti-CFLAR / FLIP Antibody (C-Terminus, Magnetic beads) LS-C171699

Catalog	Size	Price
LS-C171699-100	100 µg	Unavailable

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Anti-CFLAR / FLIP Antibody (aa206-222) IHC-plus™ LS-B2024

Antibody:	Rabbit Polyclonal (IgG) to Human CFLAR / FLIP
Reactivity:	Human
Application:	IHC - Paraffin, Western blot
Format:	Unconjugated

Anti-CFLAR / FLIP antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2024 concentration 10 ug/ml.

Anti-CFLAR / FLIP Antibody (aa1-376, clone 5D8) LS-C93734

Antibody:	Mouse Monoclonal [clone 5D8] (IgG3) to Human CFLAR / FLIP
Reactivity:	Human
Application:	Western blot, ELISA
Format:	Unconjugated

Cell lysates of mouse kidney, MCF7 and rat spleen (40 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human FLIP (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-CFLAR / FLIP Antibody (aa191-209) IHC-plus™ LS-B3187

Antibody:	Rabbit Polyclonal (IgG) to Human CFLAR / FLIP
Reactivity:	Human, Mouse
Application:	IHC - Paraffin, ICC, Western blot, ELISA
Format:	Unconjugated

Anti-CFLAR / FLIP antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3187 concentration 5 ug/ml.

Anti-CFLAR / FLIP Antibody (clone 2F12) IHC-plus™ LS-B5753

Antibody:	Mouse Monoclonal [clone 2F12] (IgG2a,k) to Human CFLAR / FLIP
Reactivity:	Human
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Anti-CFLAR / FLIP antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5753 concentration 10 ug/ml.

Anti-CFLAR / FLIP Antibody (aa1-480, clone NF6) LS-C344945

Antibody:	Mouse Monoclonal [clone NF6] (IgG1) to Human CFLAR / FLIP
Reactivity:	Human
Application:	IHC - Paraffin, ICC, Western blot
Format:	Unconjugated

Antibody:	Rabbit Polyclonal to Human CFLAR / FLIP
Reactivity:	Human, Mouse, Rat
Application:	Immunoprecipitation (applications tested for the base form of this product only)
Format:	Magnetic beads Conjugated

This image was taken for the unconjugated form of this product. Other forms have not been tested.

Details

Target:	Human CFLAR / FLIP
Host:	Rabbit
Reactivity:	Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Magnetic beads. Also available Unconjugated or conjugated with Sepharose.
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Immunoprecipitation
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:	CFLAR / FLIP antibody was raised against synthetic peptide corresponding to a sequence mapping at the C-terminal of human FLIP-L, identical to the related mouse sequence.
Epitope:	C-Terminus
Specificity:	Human, mouse, rat. No cross reactivity with other proteins.

Packaging

Presentation:	1 mg/ml magnetic beads in PBS, pH 7.2, 0.05 mg sodium azide
Storage:	stable 4°C
Restrictions:	For research use only.

About CFLAR / FLIP

Uniprot: O15519 NCBI: NM_003879 NP_003870.4

Synonyms: CFLAR Antibody, C-FLIPR Antibody, C-FLIPS Antibody, C-FLIP Antibody, CASP8AP1 Antibody, Cflip Antibody, CLARP Antibody, CASH Antibody, Caspase homolog Antibody, Caspase-eight-related protein Antibody, Flice inhibitory protein Antibody, I-FLICE Antibody, Inhibitor of FLICE Antibody, FLAME Antibody, FLAME1 Antibody, MRIT Antibody, Usurpin beta Antibody, C-FLIPL Antibody, Casper Antibody, FLAME-1 Antibody, FLIP Antibody, Usurpin Antibody

Description: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively.

(More About CFLAR / FLIP)