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Anti-CFLAR / FLIP Antibody (C-Terminus, Magnetic beads) LS-C171699
(applications tested for the base form of this product only)
Specificity and Use
CFLAR / FLIP antibody was raised against synthetic peptide corresponding to a sequence mapping at the C-terminal of human FLIP-L, identical to the related mouse sequence.
C-Terminus
Human, mouse, rat. No cross reactivity with other proteins.
Packaging
1 mg/ml magnetic beads in PBS, pH 7.2, 0.05 mg sodium azide
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively.