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Anti-APAF1 / APAF-1 Antibody (N-Terminus, Magnetic beads) LS-C172085

Catalog Size Price
LS-C172085-100 100 µg Unavailable

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84 APAF1 / APAF-1 Antibodies

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Formalin-fixed, paraffin-embedded tissue sections of human brain tumors stained for Apaf 1 expression using LS-C148201 at 1:2000. A. Gemistocytoma (grade II). B. Anaplastic glioma. A high level of Apaf 1was observed in the gemistocytoma whereas a low level was seen in the more malignant anaplastic glioma. Hematoxylin-Eos in counterstain.
Anti-APAF1 / APAF-1 Antibody (aa1-464, clone 2E12, Low Endotoxin) IHC-plus™ LS-B12884
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Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.

100% Guaranteed
Rabbit Polyclonal to Human APAF1 / APAF-1
Human, Mouse, Rat
Immunoprecipitation (applications tested for the base form of this product only)
Magnetic beads Conjugated

Details

Human APAF1 / APAF-1
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Magnetic beads. Also available Unconjugated or conjugated with Sepharose.
Immunoaffinity purified
Unmodified

Applications

  • Immunoprecipitation
  • (applications tested for the base form of this product only)

Specificity and Use

APAF1 / APAF-1 antibody was raised against synthetic peptide corresponding to a sequence at the N-terminal of human APAF1, identical to the related rat and mouse sequence.
N-Terminus
Human, rat, mouse. No cross reactivity with other proteins.

Packaging

1 mg/ml magnetic beads in PBS, pH 7.2, 0.05 mg sodium azide
Store at 4°C.
For research use only.

About APAF1 / APAF-1

O14727 NM_013229 NP_037361.1

APAF1 Antibody, APAF-1 Antibody, CED4 Antibody, KIAA0413 Antibody

Apaf1 has been described as the core of the apoptosome. Deficiency in murine Apaf1 leads to embryonic lethality with a phenotype affecting many aspects of developmental apoptosis. In the developing brain, Apaf1 is a death regulator of the neuronal founder cells. Combined intercrosses of mouse lines mutant for members of the mitochondrial death pathway are providing us with some clues about the relative regulation existing among neuronal cell populations.

Immunohistochemistry

 This image was taken for the unconjugated form of this product. Other forms have not been tested.
This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

 This image was taken for the unconjugated form of this product. Other forms have not been tested.
This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 5/27/2018

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