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THBS1 / Thrombospondin-1

thrombospondin 1

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors.

Gene Name: thrombospondin 1
Synonyms: THBS1, Thrombospondin-1, Thrombospondin-1p180, TSP, TSP1, THBS-1, THBS, Thrombospondin 1, TSP-1
Target Sequences: NM_003246 NP_003237.2 P07996

Publications (6)

1
Activation of the ROCK1 Branch of the Transforming Growth Factor-² Pathway Contributes to RAGE-Dependent Acceleration of Atherosclerosis in Diabetic ApoE-Null Mice. De-xiu Bu, Vivek Rai, Xiaoping Shen, Rosa Rosario, Yan Lu, Vivette D'Agati, Shi Fang Yan, Richard A. Friedman, Edem Nuglozeh and Ann Marie Schmidt. Circulation research. 2010 106:1040-51. (WB; Mouse) [Full Text Article] [PubMed:20133903] [PMC:PMC2848909]
2
Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Schips TG, Vanhoutte D, Vo A, Correll RN, Brody MJ, Khalil H, Karch J, Tjondrokoesoemo A, Sargent MA, Maillet M, Ross RS, Molkentin JD. Nature communications. 2019 January;10:76. [Full Text Article] [PubMed:30622267] [PMC:PMC6325143] Related Antibodies: LS-B4155.
3
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Wiley CD, Liu S, Limbad C, Zawadzka AM, Beck J, Demaria M, Artwood R, Alimirah F, Lopez-Dominguez JA, Kuehnemann C, Danielson SR, Basisty N, Kasler HG, Oron TR, Desprez PY, Mooney SD, Gibson BW, Schilling B, Campisi J, Kapahi P. Cell reports. 2019 September;28:3329-3337.e5. [Full Text Article] [PubMed:31553904] [PMC:PMC6907691]
4
Coding transcriptome analyses reveal altered functions underlying immunotolerance of PEG-fused rat sciatic nerve allografts. Tyler A Smith, Cameron L Ghergherehchi, Haley O Tucker, George D Bittner. Journal of neuroinflammation. 2020 October;17:287. [Full Text Article] [PubMed:33008419] [PMC:PMC7532577] Related Antibodies: LS-C137099.
5
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity10<sup> Campus Moulin de la Housse, Plateau Technique Mobile en Cytométrie Environnementale MOBICYTE, UFR Sciences Exactes et Naturelles, Université de Reims Champagne-Ardenne/INERIS, 51000 Reims, France. Albin Jeanne , Thomas Sarazin , Magalie Charlé , Catherine Moali, Caroline Fichel, Camille Boulagnon-Rombi , Maïté Callewaert, Marie-Christine Andry, Eric Diesis, Frédéric Delolme , Damien Rioult, Stéphane Dedieu. Cancers. 2021 Oct;13:5019. [Full Text Article] [PubMed:34638503] [PMC:PMC8508526]
6
Thrombospondin-1 aggravates colonic mucosal inflammatory injuries via promoting the differentiation of CD11c+<sup> macrophages with lysosomal activity limited in colitis. Ping Tao, Beiping Zhang, Jiang Lin, Shiying Wang. Annals of translational medicine. 2021 December;9:1738. [Full Text Article] [PubMed:35071432] [PMC:PMC8743729]
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THBS1 / Thrombospondin-1 (167)
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THBS1 / Thrombospondin-1 Antibody - Anti-THBS1 / Thrombospondin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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THBS1 / Thrombospondin-1 Goat anti-Human Polyclonal (aa19-32) Antibody
Mouse, Bovine, Pig, Horse, Human, Monkey
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
THBS1 / Thrombospondin-1 Antibody - Anti-Thrombospondin antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
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THBS1 / Thrombospondin-1 Mouse anti-Human Monoclonal (Azide-free) (A6.1) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Pig, Horse, Human
Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free
50 µl/$485
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THBS1 / Thrombospondin-1 Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Pig, Horse, Human
Flo, IF, IHC, IP, WB
PE Conjugated
100 µl/$1,112
THBS1 / Thrombospondin-1 Antibody - Anti-Thrombospondin antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
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THBS1 / Thrombospondin-1 Mouse anti-Human Monoclonal (Azide-free) Antibody
Human
IHC, IHC-P, WB
Unconjugated, Azide-free
50 µl/$485
THBS1 / Thrombospondin-1 Antibody
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THBS1 / Thrombospondin-1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
100 µl/$332
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$715
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$782
THBS1 / Thrombospondin-1 Protein - Recombinant Thrombospondin 1 By SDS-PAGE
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E. coli
His
26.3 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
THBS1 / Thrombospondin-1 Protein - Recombinant Thrombospondin 1 By SDS-PAGE
Select
E. coli
His, N-Terminal
23.4 kDa
10 µg/$279; 50 µg/$427; 200 µg/$852; 1 mg/$1,950; 5 mg/$2,983; 2 mg/$2,136
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Microplate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
THBS1 / Thrombospondin-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$749
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THBS1 / Thrombospondin-1 Mouse anti-Human Monoclonal (A4.1) Antibody
Chicken, Bovine, Mouse, Rat, Human
Block, Flo, IF, WB
Unconjugated
500 µl/$537
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$779
THBS1 / Thrombospondin-1 Antibody - Formalin-fixed, paraffin-embedded human tonsil stained with Thrombospondin antibody.
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THBS1 / Thrombospondin-1 Mouse anti-Human Monoclonal (A6.1) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Pig, Horse, Human
IF, IHC, IP, WB
Unconjugated
0.1 ml/$293; 0.5 ml/$538; 1 ml/$832
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$764
THBS1 / Thrombospondin-1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
THBS1 / Thrombospondin-1 Protein - Recombinant Thrombospondin 1 By SDS-PAGE
Select
E. coli
His
18.8 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
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THBS1 / Thrombospondin-1 Mouse anti-Bovine Monoclonal Antibody
Bovine, Human
ELISA, IHC
Unconjugated
100 µl/$1,167
THBS1 / Thrombospondin-1 Antibody - Western blot analysis of extracts of various cells.
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THBS1 / Thrombospondin-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
THBS1 / Thrombospondin-1 Antibody - THBS1 antibody HEK293 lysate (10 ug protein in RIPA buffer) overexpressing Human THBS1 with C-terminal MYC tag probed with (1 ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with (1 ug/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence.
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THBS1 / Thrombospondin-1 Goat anti-Human Polyclonal (aa475-487) Antibody
Rabbit, Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
THBS1 / Thrombospondin-1 Antibody - Western blot of THBS1 / Thrombospondin-1 antibody.
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THBS1 / Thrombospondin-1 Rabbit anti-Mouse Polyclonal (aa957-1129) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
THBS1 / Thrombospondin-1 Antibody - Western Blot; Sample: Recombinant THBS1, Mouse.
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THBS1 / Thrombospondin-1 Rabbit anti-Mouse Polyclonal (aa515-671) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
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THBS1 / Thrombospondin-1 Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Mouse, Rat, Human
ELISA
Biotin Conjugated, Preservative Free
50 µg/$343
Viewing 1-25 of 167 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).