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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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Proenkephalin / PENK

proenkephalin

Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.

Gene Name: proenkephalin
Family/Subfamily: Endogenous opioids , not assigned-Endogenous opioids
Synonyms: PENK, Enkephalin A, Met enkephalin, Preproenkephalin, Proenkephalin, Proenkephalin-A
Target Sequences: NM_006211 NP_006202.1 P01210

Publications (2)

1
Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics. Harris KD, Hochgerner H, Skene NG, Magno L, Katona L, Bengtsson Gonzales C, Somogyi P, Kessaris N, Linnarsson S, Hjerling-Leffler J. PLoS biology. 2018 June;16:e2006387. (Rat) [Full Text Article] [PubMed:29912866] [PMC:PMC6029811] Related Antibodies: LS-C23084.
2
Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus. Abdi A, Mallet N, Mohamed FY, Sharott A, Dodson PD, Nakamura KC, Suri S, Avery SV, Larvin JT, Garas FN, Garas SN, Vinciati F, Morin S, Bezard E, Baufreton J, Magill PJ. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015 35:6667-88. (IHC; Rat) [Full Text Article] [PubMed:25926446] [PMC:PMC4412890] Related Antibodies: LS-C23084.

Viewing 1-25 of 43 items
Proenkephalin / PENK Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
Select
Neuroscience
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
Proenkephalin / PENK Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
Proenkephalin / PENK Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
Proenkephalin / PENK Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $385.00
Proenkephalin / PENK Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100µl   1mg/ml   $385.00
Select
(2) Publication(s)
Rabbit Polyclonal (IgG) to Rat Proenkephalin / PENK
Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human
IHC, IHC-Fr
Unconjugated
50µl   $435.00
Proenkephalin / PENK Antibody - Goat Anti-Proenkephalin (mouse) Antibody (0.02µg/ml) staining of PFA-perfused cryosection of Mouse Stria terminalis. HRP-staining with Ni-DAB after Biotin-SP-anti-goat amplification. Data obtained by Prof. Erik Hrabovszky, Inst, Exp, Med., Budapest, Hungary.
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Goat Polyclonal to Mouse Proenkephalin / PENK
Mouse, Rat
IHC-Fr, Peptide-ELISA
Unconjugated
100µg   0.5mg/ml   $405.00
Select
Rabbit Polyclonal (IgG) to Cat Proenkephalin / PENK
Rat, Pig, Cat
IF, IHC, IHC-Fr, IHC-P
Unconjugated
50µl   $695.00
Select
Mouse Monoclonal (IgG) to Rat Proenkephalin / PENK
Rabbit, Guinea pig, Rat, Hamster
ICC, IHC, IHC-Fr
Unconjugated
100µl   $575.00
Select
Mouse Monoclonal (IgG) to Human Proenkephalin / PENK
Human
IHC, RIA
Unconjugated
500µl   $1,080.00
Proenkephalin / PENK Antibody - PENK antibody immunohistochemistry of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human Proenkephalin / PENK
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
ELISA, ICC, IHC, RIA
Unconjugated
100µl   $435.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Proenkephalin / PENK Antibody - Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200.
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Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Rat Proenkephalin / PENK
Rat
ICC, IF
Unconjugated
50µg   $445.00
Proenkephalin / PENK Antibody - Western Blot analysis of PENK expression in transfected 293T cell line by PENK monoclonal antibody (M04), clone 9E7.Lane 1: PENK transfected lysate (Predicted MW: 29.48 KDa).Lane 2: Non-transfected lysate.
Select
Mouse Monoclonal [clone 9E7] (IgG1,k) to Human Proenkephalin / PENK
Human
ELISA, WB
Unconjugated
100µg   $365.00
Select
Rabbit Polyclonal to Cat Proenkephalin / PENK
Pig, Cat
IHC, IHC-Fr, IHC-P
Unconjugated
50µl   $665.00
Select
Rabbit Polyclonal to Human Proenkephalin / PENK
Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
Select
Rabbit Polyclonal (IgG) to Bovine Proenkephalin / PENK
Bovine
IHC, IHC-Fr
Unconjugated
100µl   $455.00

Viewing 1-25 of 43 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).