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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ITGA6/Integrin Alpha 6/CD49f

integrin, alpha 6

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: integrin, alpha 6
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B
Target Sequences: NM_000210 NP_000201.2 P23229

Publications (7)

1
Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. Stepp MA, Liu Y, Pal-Ghosh S, Jurjus RA, Tadvalkar G, Sekaran A, Losicco K, Jiang L, Larsen M, Li L, Yuspa SH. Journal of cell science. 2007 120:2851-63. [PubMed:17666434] Related Antibodies: LS-C41344.
2
Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:5774-9. (IHC) [PubMed:18391223] [PMC:PMC2311360] Related Antibodies: LS-C41344.
3
Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP. Science signaling. 2009 2:ra2. [PubMed:19176516] [PMC:PMC2906144] Related Antibodies: LS-C41344.
4
Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Xu T, Xu Y, Liao CP, Lau R, Goldkorn A. Molecular cancer therapeutics. 2010 9:438-49. [PubMed:20124445] [PMC:PMC2820598] Related Antibodies: LS-C41344.
5
Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus MC, Tetta C, Bussolati B, Camussi G. Cancer research. 2011 71:5346-56. [PubMed:21670082] Related Antibodies: LS-C41344.
6
Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Lai KP, Yamashita S, Vitkus S, Shyr CR, Yeh S, Chang C. Molecular endocrinology (Baltimore, Md.). 2012 26:52-66. [PubMed:22135068] [PMC:PMC3248327] Related Antibodies: LS-C41344.
7
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Jo M, Eastman BM, Webb DL, Stoletov K, Klemke R, Gonias SL. Cancer research. 2010 70:8948-58. [PubMed:20940399] [PMC:PMC2970644] Related Antibodies: LS-C41344.
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Filtered by: None
Target
ITGA6/Integrin Alpha 6/CD49f (164)
Reactivity
Human (138)
Mouse (63)
Rat (21)
Bat (14)
Bovine (14)
Chicken (7)
Cynomolgus (2)
Cynomolgus monkey (1)
Dog (28)
Guinea pig (7)
Hamster (14)
Horse (21)
Monkey (40)
Pig (20)
Sheep (6)
Application
IHC (116)
IHC-Fr (24)
IHC-P (32)
WB (69)
Flo (76)
ELISA (23)
Func (1)
ICC (19)
IF (14)
IP (47)
Peptide-ELISA (1)
Host
rabbit (73)
mouse (57)
goat (1)
rat (33)
Isotype
IgG (39)
IgG1 (24)
IgG1,k (7)
IgG2 (1)
IgG2,k (7)
IgG2a (31)
IgG2a,k (3)
IgG2b (9)
Clonality
monoclonal mc (91)
polyclonal pc (73)
Clone
129CT49.6.5 (4)
450-30A (4)
4C1 (1)
4F10 (4)
6B4 (1)
BQ16 (5)
CLB-701 (1)
GoH3 (5)
Mab-5A (3)
NKI-GoH3 (7)
Format
AP Conjugated (13)
APC (1)
APC Conjugated (11)
Azide-free (7)
Biotin Conjugated (18)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (24)
HRP Conjugated (15)
Low Endotoxin (1)
PE Conjugated (18)
RPE Conjugated (4)
Unconjugated (59)
Epitope
Internal (14)
N-Terminus (14)
aa1043-1072 (8)
aa903-1073 (8)
900-980 aa, C-terminal (1)
C-Terminus (1)
Cytoplasmic Domain (1)
aa1082-1110 (1)
aa324-620 (1)
aa50-100 (1)
aa565-872 (1)
aa750-800 (1)
aa923-972 (1)
aa93-148 (1)
Publications
No (163)
Yes (1)
Showing 1-25 of 164 results

IHC-plus™ ITGA6/Integrin Alpha 6/CD49f Antibody (N-Terminus) LS-A8767
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ITGA6 / CD49f antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ ITGA6/Integrin Alpha 6/CD49f Antibody (aa324-620) LS-B11070
Mouse Monoclonal (IgG1) to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200µl  $425.00
Anti-ITGA6/Integrin Alpha 6/CD49f antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Confocal immunofluorescence of ITA6 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).

IHC-plus™ ITGA6/Integrin Alpha 6/CD49f Antibody (Internal) LS-A8768
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ITGA6 / CD49f antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ ITGA6/Integrin Alpha 6/CD49f Antibody (N-Terminus) LS-A8770
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ITGA6 / CD49f antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ ITGA6/Integrin Alpha 6/CD49f Antibody (Internal) LS-A8769
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Horse, Human
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ITGA6 / CD49f antibody IHC of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ ITGA6/Integrin Alpha 6/CD49f Antibody (aa1043-1072) LS-B3626
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Human
IF, IHC, IHC-P, WB
Unconjugated
200µl  $425.00
Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ITGA6 / CD49f antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, RPE) LS-C45281
Rat Monoclonal [clone NKI-GoH3] (IgG2a) to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo
RPE Conjugated
0.1mg  $405.00

ITGA6/Integrin Alpha 6/CD49f Antibody (clone GoH3) LS-C41344
Publications (7)
Publications (7)
Rat Monoclonal [clone GoH3] (IgG2a) to Human ITGA6/Integrin Alpha 6/CD49f
Mouse, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100µg 0.5mg/ml  $225.00
MDA-MB-231 breast cancer cells were stained with anti-CD49f (clone GoH3) followed by DyLight 649 Goat anti-rat Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.
Human peripheral blood lymphocytes stained with purified GoH3, followed by anti-rat IgGs FITC

ITGA6/Integrin Alpha 6/CD49f Antibody (clone Mab-5A) LS-C187479
Mouse Monoclonal [clone Mab-5A] (IgG1) to Rat ITGA6/Integrin Alpha 6/CD49f
Rat
ELISA, Flo, IF, IHC, IHC-Fr
Unconjugated
0.25mg  $395.00

ITGA6/Integrin Alpha 6/CD49f Antibody (clone Mab-5A, RPE) LS-C187480
Mouse Monoclonal [clone Mab-5A] (IgG1) to Rat ITGA6/Integrin Alpha 6/CD49f
Rat
Flo
RPE Conjugated
100tst  $415.00

ITGA6/Integrin Alpha 6/CD49f Antibody LS-C35650
Mouse Monoclonal (IgG1) to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo, IHC, WB
Unconjugated
100µg  $455.00

ITGA6/Integrin Alpha 6/CD49f Antibody (aa1082-1110) LS-C168548
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human brain tissue reacted with CD49f Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of CD49f Antibody in 293 cell line lysates (35 ug/lane). CD49f (arrow) was detected using the purified antibody.

ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, Low Endotoxin) LS-C188732
Rat Monoclonal [clone NKI-GoH3] (IgG2a) to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo, IHC, IHC-Fr, IP
Unconjugated, Low Endotoxin
0.5mg  $590.00

ITGA6/Integrin Alpha 6/CD49f Antibody (clone BQ16, Biotin) LS-C134738
Mouse Monoclonal [clone BQ16] (IgG1) to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo, IHC, WB
Biotin Conjugated
100µg 1mg/ml  $345.00

ITGA6/Integrin Alpha 6/CD49f Antibody (clone BQ16, FITC) LS-C134739
Mouse Monoclonal [clone BQ16] (IgG1) to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo, IHC, WB
FITC Conjugated
120tst  $345.00
Flow cytometry of ITGA6/Integrin Alpha 6/CD49f antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.

ITGA6/Integrin Alpha 6/CD49f Antibody (clone BQ16, RPE) LS-C134740
Mouse Monoclonal [clone BQ16] (IgG1) to Human ITGA6/Integrin Alpha 6/CD49f
Human
Flo, IHC, WB
RPE Conjugated
120tst  $415.00

ITGA6/Integrin Alpha 6/CD49f Antibody (clone 4C1) LS-C197543
Mouse Monoclonal [clone 4C1] (IgG2a,k) to Human ITGA6/Integrin Alpha 6/CD49f
Human
ELISA, WB
Unconjugated
100µg  $365.00
Detection limit for recombinant GST tagged ITGA6 is approximately 0.1 ng/ml as a capture antibody.

ITGA6/Integrin Alpha 6/CD49f Antibody (clone GoH3, Biotin) LS-C106980
Rat Monoclonal [clone GoH3] (IgG2a,k) to Human ITGA6/Integrin Alpha 6/CD49f
Mouse, Human
Flo
Biotin Conjugated
25µg 0.5mg/ml  $225.00; 100µg  $315.00
Staining of normal human peripheral blood cells with 0.25 ug of Biotin Rat IgG2a isotype control (open histogram) or 0.125 ug of Biotin anti-human/mouse CD49f (Integrin alpha 6) (colored histogram) followed by SAv-PE. Cells in the lymphocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

ITGA6/Integrin Alpha 6/CD49f Antibody (clone 4F10) LS-C13713
Mouse Monoclonal [clone 4F10] (IgG2b) to Mouse ITGA6/Integrin Alpha 6/CD49f
Mouse, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100µg  $620.00

ITGA6/Integrin Alpha 6/CD49f Antibody LS-C24764
Mouse Monoclonal (IgG) to Chicken ITGA6/Integrin Alpha 6/CD49f
Chicken
ICC, IHC, IP, WB
Unconjugated
100µg  $680.00

ITGA6/Integrin Alpha 6/CD49f Antibody LS-C123061
Rat Monoclonal (IgG2a) to Human ITGA6/Integrin Alpha 6/CD49f
Mouse, Dog, Pig, Cynomolgus, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100µg  $515.00

ITGA6/Integrin Alpha 6/CD49f Antibody LS-C497632
Rabbit Monoclonal to Human ITGA6/Integrin Alpha 6/CD49f
Mouse, Rat, Human
IHC, WB
Unconjugated
50µl  $295.00; 100µl  $385.00; 200µl  $560.00
Immunohistochemistry of paraffin-embedded mouse stomach using ITGA6 antibodyat dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using ITGA6 antibodyat dilution of 1:100 (40x lens).

ITGA6/Integrin Alpha 6/CD49f Antibody (clone 129CT49.6.5, AP) LS-C250274
Mouse Monoclonal [clone 129CT49.6.5] (IgG1,k) to Human ITGA6/Integrin Alpha 6/CD49f
Human
ELISA, Flo, ICC, IF, IHC, WB
AP Conjugated
200µl  $740.00

ITGA6/Integrin Alpha 6/CD49f Antibody (clone 129CT49.6.5, APC) LS-C250275
Mouse Monoclonal [clone 129CT49.6.5] (IgG1,k) to Human ITGA6/Integrin Alpha 6/CD49f
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200µl  $740.00

ITGA6/Integrin Alpha 6/CD49f Antibody (clone 129CT49.6.5, Azide-free, HRP) LS-C250276
Mouse Monoclonal [clone 129CT49.6.5] (IgG1,k) to Human ITGA6/Integrin Alpha 6/CD49f
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00
Showing 1-25 of 164 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).