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Catalog Number Size Price
LS-C45281-100 100 Tests $456 
Antibody

Monoclonal Rat anti‑Human ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI‑GoH3, RPE) LS‑C45281

Monoclonal Rat anti‑Human ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI‑GoH3, RPE) LS‑C45281

Note: This antibody replaces LS-C58622
Antibody:
ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal (RPE) (NKI-GoH3) Antibody
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified
Other formats:
Price
Catalog Number
$456
LS-C45281-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal (RPE) (NKI-GoH3) Antibody
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified
Other formats:

Specifications

Description
CD49f antibody LS-C45281 is an RPE-conjugated rat monoclonal antibody to human CD49f (ITGA6 / Integrin Alpha 6). Validated for Flow.
Target
Human ITGA6/Integrin Alpha 6/CD49f
Synonyms
ITGA6 | CD49f | CD49f antigen | Integrin alpha6B | Integrin, alpha 6 | Integrin alpha-6 precursor | VLA-6 | Integrin alpha-6 | ITGA6B
Host
Rat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Clone
NKI-GoH3
Conjugations
R. Phycoerythrin. Also available Unconjugated.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
BALB/c mouse mammary tumor cells
Specificity
Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. XXX recommend the use of MCA699XZ for this purpose.
Applications
  • Flow Cytometry (1:1 - 1:5)
  • Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 platelets in 100 ul. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGA6/Integrin Alpha 6/CD49f
P23229 NM_000210 NP_000201.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/8/2022