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IRF5

interferon regulatory factor 5

IRF5 is a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.

Gene Name: interferon regulatory factor 5
Synonyms: IRF5, Interferon regulatory factor 5, IRF-5, SLEB10, IBD14
Target Sequences: NM_002200 NP_116032.1 Q13568

Publications (1)

1
Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers. Zhang F, Parayath NN, Ene CI, Stephan SB, Koehne AL, Coon ME, Holland EC, Stephan MT. Nature communications. 2019 September;10:3974. [Full Text Article] [PubMed:31481662] [PMC:PMC6722139]

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Products
Antibodies (76)
Primary (76)
IRF5 (76)
Human (59)
Mouse (38)
Rat (23)
Bovine (7)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (3)
Horse (5)
Monkey (7)
Pig (4)
Rabbit (8)
Zebrafish (3)
IHC (16)
IHC-P (7)
WB (69)
Flo (2)
ChrIP (1)
ELISA (18)
ICC (1)
IF (7)
IP (5)
Peptide-ELISA (2)
rabbit (63)
mouse (11)
goat (1)
sheep (1)
IgG (32)
IgG1 (6)
IgG1,k (2)
IgG2a (3)
monoclonal mc (11)
polyclonal pc (65)
10T1 (2)
2D4 (1)
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APC (2)
APC Conjugated (3)
Biotin Conjugated (9)
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Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (3)
Unconjugated (39)
aa136-475 (8)
aa3-250 (8)
N-Terminus (4)
aa121-170 (4)
aa257-306 (4)
aa395-444 (4)
Internal (1)
Ser172 (1)
aa175-225 (1)
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aa275-325 (1)
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aa456-472 (1)
aa503-514 (1)
aa81-108 (1)
No (76)
IRF5 Antibody - Immunoperoxidase of monoclonal antibody to IRF5 on formalin-fixed paraffin-embedded human testis. [antibody concentration 0.8 ug/ml]
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IRF5 Mouse anti-Human Monoclonal (2D4) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$423
IRF5 Antibody - Immunoperoxidase of monoclonal antibody to IRF5 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 1.5 ug/ml]
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IRF5 Mouse anti-Human Monoclonal (2G9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
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IRF5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
IRF5 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-IRF5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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IRF5 Mouse anti-Human Monoclonal (OTI1G7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
IRF5 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-IRF5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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IRF5 Mouse anti-Human Monoclonal (Carrier-free) (OTI1G7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
IRF5 Antibody - IRF5 antibody Western blot of SH-SYSY lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IRF5 Rabbit anti-Human Polyclonal (aa395-444) Antibody
Human
WB
Unconjugated
100 µl/$424
IRF5 Antibody - Confocal immunofluorescence of IRF5 Antibody with A549 cell followed by Alexa Fluor 489-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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IRF5 Rabbit anti-Human Polyclonal (aa81-108) Antibody
Human
Flo, IF, WB
Unconjugated
400 µl/$393
IRF5 Antibody - Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100
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IRF5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
IRF5 Antibody - The extracts of Ramos, THP-1, A20 and NIH3T3 were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human IRF5antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
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IRF5 Mouse anti-Human Monoclonal (10T1) Antibody
Human
ELISA, ICC, IHC, IP, WB
Unconjugated
50 µl/$303; 100 µl/$365
IRF5 Antibody - Immunofluorescence analysis of HeLa cells using IRF5 antibody. Blue: DAPI for nuclear staining.
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IRF5 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
IRF5 Antibody
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IRF5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
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IRF5 Rabbit anti-Mouse Polyclonal (Ser172) Antibody
Mouse, Rat
ELISA, IP, WB
Unconjugated
100 µl/$688
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IRF5 Rabbit anti-Human Polyclonal (aa275-325) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
IRF5 Antibody - Western blot of Mouse Heart. Irf5 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IRF5 Rabbit anti-Mouse Polyclonal (aa257-306) Antibody
Mouse
WB
Unconjugated
100 µl/$424
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IRF5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$331
IRF5 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using IRF5 Polyclonal Antibody at dilution of 1:25(×200)
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IRF5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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IRF5 Mouse anti-Human Monoclonal (aa176-240) (10T1) Antibody
Human
ELISA, IHC-P, IP, WB
Unconjugated
0.1 mg/$511
IRF5 Antibody - IRF5 antibody IHC-paraffin. IHC(P): Mouse Spleen Tissue.
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IRF5 Rabbit anti-Human Polyclonal (aa442-472) Antibody
Rabbit, Mouse, Rat, Horse, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
IRF5 Antibody - Staining (2 ug/ml) of A549 lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
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IRF5 Goat anti-Human Polyclonal (aa503-514) Antibody
Human
ChrIP, IHC, Peptide-ELISA, WB
Unconjugated
100 µg/$503
IRF5 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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IRF5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IRF5 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
IRF5 Antibody - Western blot of IRF5 pAb in extracts from Jurkat and A549 cells.
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IRF5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
IRF5 Antibody - Western blot analysis of extracts of various cell lines, using IRF5 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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IRF5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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IRF5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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IRF5 Sheep anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$930
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).