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GLO1 / Glyoxalase I

glyoxalase I

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.

Gene Name: glyoxalase I
Synonyms: GLO1, Aldoketomutase, Glx I, Glyoxalase domain containing 1, Glyoxalase I, Lactoyl glutathione lyase, Lactoylglutathione lyase, GLOD1, Methylglyoxalase, Ketone-aldehyde mutase, GLYI
Target Sequences: NM_006708 NP_006699.2 Q04760

Publications (2)

1
Glyoxalase I activity and immunoreactivity in the aging human lens. Mailankot M, Padmanabha S, Pasupuleti N, Major D, Howell S, Nagaraj RH. Biogerontology. 2009 10:711-20. [PubMed:19238574] [PMC:PMC3560407]
2
Opposing roles of RAGE and Myd88 signaling in extensive liver resection. Zeng S, Zhang QY, Huang J, Vedantham S, Rosario R, Ananthakrishnan R, Yan SF, Ramasamy R, DeMatteo RP, Emond JC, Friedman RA, Schmidt AM. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2012 26:882-93. [PubMed:22075646] [PMC:PMC3365861]

☰ Filters
Products
Antibodies (48)
Primary (48)
GLO1 / Glyoxalase I (48)
Human (36)
Mouse (21)
Rat (8)
Chicken (3)
Gibbon (3)
Guinea pig (3)
Monkey (3)
Yeast (4)
Zebrafish (3)
IHC (13)
IHC-P (11)
WB (43)
Flo (1)
ELISA (18)
ICC (6)
IF (8)
IP (4)
Peptide-ELISA (1)
rabbit (37)
mouse (11)
Product Group
IHCPlus (3)
IgG (20)
IgG1 (5)
IgG1,k (5)
IgG2b,k (1)
monoclonal mc (11)
polyclonal pc (37)
4C12 (1)
CPTC-GLO1-1 (3)
Glo1a (5)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
BSA-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Ready-to-Use (1)
Unconjugated (29)
aa7-182 (8)
aa1-184 (4)
aa35-84 (4)
aa83-184 (2)
aa1-50 (1)
aa134-184 (1)
aa23-51 (1)
No (48)
GLO1 / Glyoxalase I Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (aa83-184) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
GLO1 / Glyoxalase I Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (aa83-184) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
GLO1 / Glyoxalase I Antibody - Anti-GLO1 / Glyoxalase I antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal (aa1-184) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
GLO1 / Glyoxalase I Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with GLO1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal (aa23-51) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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GLO1 / Glyoxalase I Rabbit anti-Yeast Polyclonal Antibody
Yeast
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
GLO1 / Glyoxalase I Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using GLO1 Polyclonal Antibody at dilution of 1:50.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
GLO1 / Glyoxalase I Antibody - Immunohistochemistry of paraffin-embedded mouse kidney tissue.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
GLO1 / Glyoxalase I Antibody - IHC analysis of GLO1 using anti-GLO1 antibody. GLO1 was detected in paraffin-embedded section of mouse spleen tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-GLO1 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
GLO1 / Glyoxalase I Antibody - GLO1 Antibody (Glo1a) - Immunostaining of human retinal endothelial cells. Immunoreactivity for hGlx-1 was detected in human retinal endothelial cells stained with Glo1a mAb using anti mouse IgG Texas Red as secondary Ab. The cells were counter stained with phalloidin (green) and DAPI (blue), nuclear stain. No reactivity was detected in control cells, stained without Go1a mAb.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (Glo1a) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
0.1 ml/$386
GLO1 / Glyoxalase I Antibody - GLO1 Antibody (Glo1a) - Immunostaining of human retinal endothelial cells. Immunoreactivity for hGlx-1 was detected in human retinal endothelial cells stained with Glo1a mAb using anti mouse IgG Texas Red as secondary Ab. The cells were counter stained with phalloidin (green) and DAPI (blue), nuclear stain. No reactivity was detected in control cells, stained without Go1a mAb.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (Biotin) (Glo1a) Antibody
Human
ELISA, ICC, IF, WB
Biotin Conjugated
0.1 ml/$416
GLO1 / Glyoxalase I Antibody - GLO1 Antibody (Glo1a) - Immunostaining of human retinal endothelial cells. Immunoreactivity for hGlx-1 was detected in human retinal endothelial cells stained with Glo1a mAb using anti mouse IgG Texas Red as secondary Ab. The cells were counter stained with phalloidin (green) and DAPI (blue), nuclear stain. No reactivity was detected in control cells, stained without Go1a mAb.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (DY488) (Glo1a) Antibody
Human
ELISA, ICC, IF, WB
DY488 Conjugated
0.1 ml/$416
GLO1 / Glyoxalase I Antibody - GLO1 Antibody (Glo1a) - Immunostaining of human retinal endothelial cells. Immunoreactivity for hGlx-1 was detected in human retinal endothelial cells stained with Glo1a mAb using anti mouse IgG Texas Red as secondary Ab. The cells were counter stained with phalloidin (green) and DAPI (blue), nuclear stain. No reactivity was detected in control cells, stained without Go1a mAb.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (DY650) (Glo1a) Antibody
Human
ELISA, ICC, IF, WB
DY650 Conjugated
0.1 ml/$416
GLO1 / Glyoxalase I Antibody - GLO1 Antibody (Glo1a) - Immunostaining of human retinal endothelial cells. Immunoreactivity for hGlx-1 was detected in human retinal endothelial cells stained with Glo1a mAb using anti mouse IgG Texas Red as secondary Ab. The cells were counter stained with phalloidin (green) and DAPI (blue), nuclear stain. No reactivity was detected in control cells, stained without Go1a mAb.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (DY550) (Glo1a) Antibody
Human
ELISA, ICC, IF, WB
DY550 Conjugated
0.1 ml/$416
GLO1 / Glyoxalase I Antibody - Immunohistochemistry of paraffin-embedded human prostate tissue using antibody at 1:100 dilution.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal (aa1-184) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
GLO1 / Glyoxalase I Antibody - Immunohistochemistry of paraffin-embedded human prostate tissue using antibody at 1:100 dilution.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal (aa1-184) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
GLO1 / Glyoxalase I Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IP, WB
Unconjugated
100 µl/$412
GLO1 / Glyoxalase I Antibody - Immunohistochemical analysis of Glyoxalase I staining in mouse kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
GLO1 / Glyoxalase I Antibody - 1:100 staining human kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
Select
GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
GLO1 / Glyoxalase I Antibody - IHC testing of FFPE human prostate carcinoma stained with GLO1 antibody. Required HIER: boiling tissue sections in 10mM citrate buffer, pH6, for 10-20 min followed by cooling at RT for 20 min.
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (CPTC-GLO1-1) Antibody
Human
IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
GLO1 / Glyoxalase I Antibody - IHC testing of FFPE human prostate carcinoma stained with GLO1 antibody. Required HIER: boiling tissue sections in 10mM citrate buffer, pH6, for 10-20 min followed by cooling at RT for 20 min.
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GLO1 / Glyoxalase I Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CPTC-GLO1-1) Antibody
Human
IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
Select
GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal (aa1-184) Antibody
Human
IP, WB
Unconjugated
100 µl/$749
GLO1 / Glyoxalase I Antibody - Detection of human GLO1/Glyoxalase I by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-GLO1/Glyoxalase Iantibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 1 second.
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GLO1 / Glyoxalase I Rabbit anti-Human Polyclonal (aa134-184) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).