Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (800) 227-6666


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

CFLAR / FLIP

CASP8 and FADD-like apoptosis regulator

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family. FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP, respectively. The human FLIP was also cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP contains two death effector domains (DEDs) and a caspase-like domain. FLIP interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors. Four splice variants of c-FLIPs have been identified and termed FLIPa, b, g, and d, respectively.

Gene Name: CASP8 and FADD-like apoptosis regulator
Family/Subfamily: Apoptosis , Cysteine C14
Synonyms: CFLAR, C-FLIPR, C-FLIPS, C-FLIP, CASP8AP1, Cflip, CLARP, CASH, Caspase homolog, Caspase-eight-related protein, Flice inhibitory protein, I-FLICE, Inhibitor of FLICE, FLAME, FLAME1, MRIT, Usurpin beta, C-FLIPL, Casper, FLAME-1, FLIP, Usurpin
Target Sequences: NM_003879 NP_003870.4 O15519

☰ Filters
Antibodies (82)
Proteins (13)
ELISA Kits (5)
Development Kit (1)
Over-Expression Lysate (6)
Primary (82)
Recombinant (7)
Sandwich (4)
CFLAR / FLIP (100)
Human (70)
Mouse (23)
Rat (14)
Chimpanzee (3)
Gibbon (3)
Monkey (5)
IHC (23)
IHC-Fr (1)
IHC-P (10)
WB (78)
Flo (3)
ELISA (17)
ICC (9)
IF (5)
IP (5)
Peptide-ELISA (3)
rabbit (64)
mouse (17)
rat (1)
Product Group
DevKit DuoPlus (1)
IHCPlus (2)
IgG (39)
IgG1 (10)
IgG2a (1)
IgG2a,k (1)
IgG2b (2)
IgG3 (3)
monoclonal mc (17)
polyclonal pc (65)
2F12 (1)
5D8 (1)
6G11A6 (1)
7A3D12 (1)
Dave-2 (1)
NF6 (2)
OTI1B1 (2)
OTI2B9 (2)
OTI2D3 (2)
OTI2H3 (2)
OTI2H8 (2)
96-Well Strip Plate (4)
Antibody Pair and Standard (1)
APC (2)
APC Conjugated (3)
Biotin Conjugated (8)
Carrier-free (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (48)
aa1-272 (10)
aa210-460 (8)
aa43-281 (8)
aa1-480 (4)
aa180-229 (4)
C-Terminus (2)
aa100-251 (2)
150-230 aa, Internal (1)
His204 (1)
N-Terminal (1)
N-Terminus (1)
aa1-376 (1)
aa145-174 (1)
aa181-230 (1)
aa191-209 (1)
aa449-465 (1)
aa75-92 (1)
No (100)
Cell Lysates (2)
Plasma (3)
Serum (3)
Tissue Homogenates (3)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (7)
Human (8)
Mouse (1)
Rat (1)
293T Cells (3)
E. coli (4)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
CFLAR / FLIP Antibody - Anti-CFLAR / FLIP antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CFLAR / FLIP Antibody - Anti-CFLAR / FLIP antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
CFLAR / FLIP Mouse anti-Human Monoclonal (2F12) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Select
CFLAR / FLIP Mouse anti-Human Monoclonal (aa1-480) (NF6) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$400; 100 µg/$487
Select
CFLAR / FLIP Mouse anti-Human Monoclonal (aa1-480) (Biotin) (NF6) Antibody
Human
ICC, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$414
CFLAR / FLIP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CFLAR / FLIP Antibody - Cell lysates of mouse kidney, MCF7 and rat spleen (40 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human FLIP (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Select
CFLAR / FLIP Mouse anti-Human Monoclonal (aa1-376) (5D8) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$303; 100 µl/$365
CFLAR / FLIP Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at dilution of 1:100.
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
CFLAR / FLIP Antibody - Immunocytochemistry of FLIP in 3T3 cells with FLIP antibody at 5 ug/ml.
Select
CFLAR / FLIP Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, ICC, WB
Unconjugated
0.1 mg/$460
CFLAR / FLIP Antibody - Immunohistochemistry of FLIP in mouse liver tissue with FLIP antibody at 5 µg/mL.
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, Flo, ICC, IF, IHC, WB
Unconjugated
0.1 mg/$460
CFLAR / FLIP Antibody - Western blot of c-FLIP antibody
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal (N-Terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CFLAR / FLIP Antibody - IHC of paraffin-embedded cervical cancer tissues using CFLAR mouse monoclonal antibody with DAB staining.
Select
CFLAR / FLIP Mouse anti-Human Monoclonal (aa100-251) (7A3D12) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
CFLAR / FLIP Antibody - Immunocytochemistry of FLIPa in Jurkat cells with FLIPa antibody at 10 ug/ml.
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1 mg/$460
CFLAR / FLIP Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
CFLAR / FLIP Antibody - Formalin-fixed and paraffin-embedded human skeletal muscle reacted with CFLAR Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal (aa145-174) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CFLAR / FLIP Antibody - IHC of paraffin-embedded cervical cancer tissues using CFLAR mouse monoclonal antibody with DAB staining.
Select
CFLAR / FLIP Mouse anti-Human Monoclonal (aa100-251) (6G11A6) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$459
CFLAR / FLIP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CFLAR / FLIP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$792
CFLAR / FLIP Protein - Recombinant CASP8 And FADD Like Apoptosis Regulator By SDS-PAGE
Select
E. coli
6His, N-terminus
32.3 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,489
CFLAR / FLIP Protein
Select
E. coli
None
100 µg/$361; 500 µg/$739; 20 µg/$261
CFLAR / FLIP Antibody - IHC of FLIP in two tissues cores from a formalin-fixed, paraffin-embedded human brain tumor microarray using Polyclonal Antibody to FLIP (long and short) at 1:2000. A, gemistocytoma (Grade II) positive for FLIP expression. B, gemistocytoma (Grade II) negative for FLIP expression. A1 and A2 are higher magnifications from A. A, A1, and A2 show expression of FLIP in the gemistocytes of the tumor. Hematoxylin-Eosin counterstain.
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal (aa75-92) Antibody
Human, Monkey
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$386
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal (150-230 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CFLAR / FLIP Antibody - IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-CFLAR mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
CFLAR / FLIP Mouse anti-Human Monoclonal (aa1-272) (OTI2H8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal (aa181-230) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
CFLAR / FLIP Rabbit anti-Human Polyclonal Antibody
Human
IHC, IP, WB
Unconjugated
50 µl/$393
Viewing 1-25 of 100 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).