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CD207 / Langerin

CD207 molecule, langerin

Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Gene Name: CD207 molecule, langerin
Synonyms: CD207, CD207 antigen, langerin, CD207 antigen, CD207 molecule, langerin, CLEC4K, Langerin
Target Sequences: NM_015717 NP_056532.4 Q9UJ71

Publications (1)

1
Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-ß1. Hahn JM, McFarland KL, Combs KA, Supp DM. Burns & trauma. 2016 4:30. (IHC; Human) [Full Text Article] [PubMed:27574697] [PMC:PMC4994224] Related Antibodies: LS-C312086.

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Antibodies (32)
Primary (32)
CD207 / Langerin (32)
Human (28)
Mouse (16)
Rat (4)
Chimpanzee (3)
Gibbon (3)
Guinea pig (3)
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IHC (4)
IHC-Fr (6)
IHC-P (9)
WB (22)
Flo (2)
ELISA (8)
IP (2)
rabbit (27)
mouse (5)
Product Group
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IgG2b (1)
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monoclonal mc (6)
polyclonal pc (26)
12D6 (3)
1C5A1 (1)
EP349 (2)
APC Conjugated (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Ready-to-Use (2)
Unconjugated (21)
C-Terminus (4)
61-110 aa, Internal (1)
aa26-44 (1)
No (31)
Yes (1)
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
CD207 / Langerin Mouse anti-Human Monoclonal (12D6) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.05 ml/$460
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD207 / Langerin Mouse anti-Human Monoclonal (12D6) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$351
CD207 / Langerin Antibody - IHC of Langerin on FFPE Skin tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD207 / Langerin Mouse anti-Human Monoclonal (Ready-to-Use) (12D6) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$336
CD207 / Langerin Antibody - IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.
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CD207 / Langerin Rabbit anti-Mouse Polyclonal (aa26-44) Antibody
Mouse, Rat, Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$386
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD207 / Langerin Antibody - Human Skin Langerhans Cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
CD207 / Langerin Mouse anti-Human Monoclonal (1C5A1) Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated
100 µl/$485
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CD207 / Langerin Rabbit anti-Human Monoclonal (EP349) Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$389; 0.5 ml/$556; 1 ml/$885
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CD207 / Langerin Rabbit anti-Human Monoclonal (Ready-to-Use) (EP349) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$325; 7 ml/$403; 15 ml/$554
CD207 / Langerin Antibody - CD207 / LANGERIN antibody Western Blot of Fetal Kidney . Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD207 / Langerin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CD207 / Langerin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
CD207 / Langerin Antibody - Human Skin Langerhans Cells: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC
Unconjugated
120 µl/$460
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
CD207 / Langerin Antibody - Western blot of CD207 antibody
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CD207 / Langerin Rabbit anti-Human Polyclonal (61-110 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CD207 / Langerin Antibody - Western blot analysis of lysate from K562 cells, using CD207 Antibody.
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IP, WB
Unconjugated
100 µl/$749
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
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CD207 / Langerin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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CD207 / Langerin Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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CD207 / Langerin Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
CD207 / Langerin Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
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CD207 / Langerin Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$937
Select
CD207 / Langerin Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$937
Select
CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
CD207 / Langerin Antibody - Western blot of extracts of HeLa cell lines, using ERBB2 antibody.
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CD207 / Langerin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
Viewing 1-25 of 32 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).