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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD207 / Langerin Antibody (aa26‑44) LS‑C735
Langerin antibody LS-C735 is an unconjugated rabbit polyclonal antibody to mouse Langerin (CD207). Validated for Flow, IHC and WB.
Catalog
Size
Price
LS-C735-100
100 µg (1 mg/ml)
$335

Popular CD207 / Langerin Products

IHC of Langerin on FFPE Skin tissue.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen
IHC of Langerin on FFPE Skin tissue. This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
CD207 / LANGERIN antibody Western Blot of Fetal Kidney . Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Rat, Guinea pig, Horse, Pig
Applications: Western blot

Product Description

Langerin antibody LS-C735 is an unconjugated rabbit polyclonal antibody to mouse Langerin (CD207). Validated for Flow, IHC and WB.

Specifications

Target
Mouse CD207 / Langerin
Synonyms
CD207, CD207 antigen, langerin, CD207 antigen, CD207 molecule, langerin, CLEC4K, Langerin
Host
Rabbit
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • IHC - Frozen
  • Western blot (1 - 3 µg/ml)
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide from mouse CD207.
Epitope
aa26-44
Specificity
Amino acids 26-44 of mouse Langerin (Genbank Accession No. CAC82936) were used as immunogen.
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CD207 / Langerin
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Q9UJ71 NM_015717 NP_056532.4


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Images

Immunohistochemistry

IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.
IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.

Western blot

Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.
Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.

Immunohistochemistry

IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.
IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.

Western blot

Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.
Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.

Immunohistochemistry

IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.
IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.

Western blot

Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.
Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.

Immunohistochemistry

IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.
IHC of skin Langerin/CD207 in formalin-fixed, paraffin-embedded human (Langerhans cells) using antibody at 2.5 ug/ml. ?Hematoxylin-Eosin counterstain.

Western blot

Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.
Western blot of langerin in mouse lung tissue lysate using 2 ug/ml of antibody. Lane 1, Without blocking peptide; Lane 2, With blocking peptide.

Requested From: United States
Date Requested: 10/15/2018

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