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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BCL2 / Bcl-2

B-cell CLL/lymphoma 2

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Gene Name: B-cell CLL/lymphoma 2
Family/Subfamily: Apoptosis
Synonyms: BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
Target Sequences: NM_000633 NP_000624.2 P10415

Publications (2)

1
BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents. Deng J, Carlson N, Takeyama K, Dal Cin P, Shipp M, Letai A. Cancer cell. 2007 12:171-85. (IP) [PubMed:17692808]
2
Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule. Zhao L, He F, Liu H, Zhu Y, Tian W, Gao P, He H, Yue W, Lei X, Ni B, Wang X, Jin H, Hao X, Lin J, Chen Q. The Journal of biological chemistry. 2012 287:1054-65. [PubMed:22065578] [PMC:PMC3256916] Related Antibodies: LS-C98842.

Filtered by: None
Target
BCL2 / Bcl-2 (298)
Reactivity
Human (270)
Mouse (79)
Rat (46)
Bovine (4)
Cat (8)
Chimpanzee (18)
Dog (32)
Gerbil (1)
Gibbon (3)
Hamster (5)
Horse (5)
Monkey (21)
Pig (22)
Rabbit (5)
Sheep (4)
Application
IHC (159)
IHC-Fr (18)
IHC-P (87)
WB (252)
Flo (72)
DB (17)
ELISA (119)
Func (1)
ICC (25)
IF (74)
IHC-Fx (8)
IP (79)
Neut (1)
Peptide-ELISA (6)
PMA (4)
SDS-PAGE (8)
Host
rabbit (172)
mouse (123)
goat (1)
pig (1)
sheep (1)
Isotype
IgG (104)
IgG1 (53)
IgG1,k (43)
IgG2a (12)
IgG2a,k (1)
IgG2b (8)
IgG2b,k (1)
Clonality
monoclonal mc (121)
polyclonal pc (169)
recombinant monoclonal rmc (8)
Clone
100/D5 (4)
100/D5 + 124 (3)
10C2 (1)
10C4 (3)
10C7 (1)
11C5 (1)
124 (6)
1E1-D10-F4 (2)
1E9 (1)
1H1 (1)
2E5 (1)
3B8 (1)
3H10 (1)
4C1 (1)
4D8-D4-E10-G3 (2)
5B1-F3-E11 (2)
5F8 (1)
5H4 (1)
7H9 (1)
83-8B (2)
8C8 (3)
8E+12 (2)
9D3 (1)
ABM3C35 (1)
ARBC2-1 (3)
AT1B5 (1)
Bcl2/100 (4)
Bcl-2/100 (6)
BCL2/1878R (2)
BCL2/2210R (2)
BCL2/782 (3)
BCL2/782 + BCL2/796 (3)
BCL2/796 (3)
BCL2/A4 (1)
BL-2 (3)
BSB-5 (BCL2/A4) (1)
E17 (1)
G1/G1-4 (1)
GF1 (1)
rBCL2/782 (2)
rBCL2/796 (2)
SPM530 (2)
TS106 (1)
Format
AP Conjugated (11)
APC (2)
APC Conjugated (14)
Azide-free (18)
Biotin Conjugated (27)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (21)
HRP Conjugated (17)
Magnetic beads Conjugated (1)
PE Conjugated (15)
Ready-to-Use (9)
RPE Conjugated (1)
Sepharose Conjugated (1)
Unconjugated (184)
Epitope
aa41-54 (24)
pSer70 (17)
pThr56 (13)
aa2-211 (9)
aa144-171 (8)
aa2-208 (8)
aa75-110 (8)
aa86-114 (8)
aa87-116 (8)
10-90 aa (4)
Internal (4)
N-Terminus (4)
aa54-103 (4)
aa85-134 (4)
aa61-76 (3)
aa67-86 (3)
pSer87 (3)
pThr69 (3)
20-100 aa (2)
40-120 aa (2)
aa1-211 (2)
30-110 aa (1)
Asp64 (1)
Pro65 (1)
aa1-195 (1)
aa4-18 (1)
aa44 (1)
aa46-95 (1)
aa49-76 (1)
aa50-100 (1)
Publications
No (297)
Yes (1)
Showing 1-25 of 298 results

BCL2 / Bcl-2 Antibody (aa46-95) IHC-plus™ LS-B6548
Rabbit Polyclonal (IgG) to Human BCL2 / Bcl-2
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-BCL2 / Bcl-2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Immunofluorescence analysis of HepG2 cells, using BCL-2 Antibody. The picture on the right is blocked with the synthesized peptide.

BCL2 / Bcl-2 Antibody (clone E17) LS-C202809
Rabbit Monoclonal [clone E17] (IgG) to Human BCL2 / Bcl-2
Human
IHC IHC-Fr IHC-P
Unconjugated
1ml  $980.00

BCL2 / Bcl-2 Antibody (aa75-110) LS-C98842
Publications (1)
Publications (1)
Rabbit Polyclonal to Human BCL2 / Bcl-2
Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human testis tissue reacted with Bcl-2 BH3 Domain Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Confocal immunofluorescence of Bcl-2 Antibody (BH3 Domain Specific) with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

BCL2 / Bcl-2 Antibody (aa41-54, clone BL-2) LS-C171045
Mouse Monoclonal [clone BL-2] (IgG1) to Human BCL2 / Bcl-2
Human
ICC IHC IHC-Fr IHC-P WB
Unconjugated
100µg 1ml 1mg/ml  $295.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (aa41-54, clone BL-2, Magnetic beads) LS-C171046
Mouse Monoclonal [clone BL-2] (IgG1) to Human BCL2 / Bcl-2
Human
IP WB
Magnetic beads Conjugated
200µl  $325.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (aa67-86) LS-C148229
Rabbit Polyclonal to Mouse BCL2 / Bcl-2
Mouse, Rat
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $335.00
Formalin-fixed paraffin-embedded section from a secondary follicle of the mouse lymph node stained for Bcl-2 expression using Polyclonal Antibody to Bcl-2 at 1:2000. A, Abundant staining is seen in the mantle zone, and little staining is seen in the germinal center. A1 is a higher magnification of A.

BCL2 / Bcl-2 Antibody LS-C675297
Rabbit Monoclonal (IgG) to Human BCL2 / Bcl-2
Mouse, Rat, Human
ELISA Flo IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $315.00; 100µl  $425.00
Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human thyroid tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.

BCL2 / Bcl-2 Antibody (clone 100/D5) LS-C357722
Mouse Monoclonal [clone 100/D5] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human, Chimpanzee
ELISA Flo IF IHC IHC-P IP WB
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00
Bcl-2 antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Bcl-2 antibody western blot.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (clone 100/D5, Azide-free) IHC-plus™ LS-B14831
Mouse Monoclonal [clone 100/D5] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human, Chimpanzee
ELISA Flo IF IHC IHC-P IP WB
Unconjugated, Azide-free
50µg 1mg/ml  $425.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Bcl-2 antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (clone 100/D5, Ready-to-Use) LS-C389441
Mouse Monoclonal [clone 100/D5] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human, Chimpanzee
ELISA Flo IF IHC IHC-P IP WB
Unconjugated, Ready-to-Use
7ml  $465.00
Bcl-2 antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Bcl-2 antibody western blot.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (aa41-54, clone 124) LS-C357724
Mouse Monoclonal [clone 124] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human, Chimpanzee
ELISA Flo IF IHC IHC-P IP WB
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00
Bcl-2 antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Bcl-2 antibody western blot.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (aa41-54, clone 124, Azide-free) LS-C389442
Mouse Monoclonal [clone 124] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human, Chimpanzee
ELISA Flo IF IHC IHC-P IP WB
Unconjugated, Azide-free
100µg 1mg/ml  $465.00
Bcl-2 antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Bcl-2 antibody western blot.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (aa41-54, clone 124, Ready-to-Use) LS-C389437
Mouse Monoclonal [clone 124] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human, Chimpanzee
ELISA Flo IF IHC IHC-P IP WB
Unconjugated, Ready-to-Use
7ml  $465.00
Bcl-2 antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Bcl-2 antibody western blot.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody LS-C413485
Mouse Monoclonal to Human BCL2 / Bcl-2
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $275.00
Immunohistochemical analysis of BCL2 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of BCL2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a FITC-conjugated secondary antibody (green) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

BCL2 / Bcl-2 Antibody (aa41-54, clone 8C8) LS-C357723
Mouse Monoclonal [clone 8C8] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human, Monkey, Chimpanzee
ELISA Flo IF IHC IHC-P IP WB
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00
Bcl-2 antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Bcl-2 antibody western blot.  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (phospho-Thr56) LS-C413176
Rabbit Polyclonal to Human BCL2 / Bcl-2
Rat, Human
ICC IF IHC IHC-P IP WB
Unconjugated
100µl 1mg/ml  $295.00
Immunohistochemical analysis of BCL2 (pT56) staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of BCL2 (pT56) staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

BCL2 / Bcl-2 Antibody (aa41-54, clone SPM530) LS-C392409
Mouse Monoclonal [clone SPM530] (IgG1,k) to Human BCL2 / Bcl-2
Dog, Pig, Human
Flo IF IHC IHC-P WB
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00
Formalin-fixed, paraffin-embedded human non-Hodgkin's lymphoma stained with anti-Bcl-2 antibody (SPM530).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Western blot of Bcl-2 in human skin using anti-Bcl-2 antibody (SPM530).  This image was taken for the unmodified form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (20-100 aa) LS-C382281
Rabbit Polyclonal (IgG) to Human BCL2 / Bcl-2
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of Bcl-2 antibody
Western blot of Bcl-2 antibody

BCL2 / Bcl-2 Antibody LS-C438
Rabbit Polyclonal (IgG) to Human BCL2 / Bcl-2
Mouse, Human
ELISA IF IHC-P WB
Unconjugated
0.1mg 1mg/ml  $365.00
IHC of human kidney using Bcl-2 antibody at 2 ug/ml.
Immunofluorescence of Bcl-2 in Human Kidney cells with Bcl-2 antibody at 10 ug/ml.

BCL2 / Bcl-2 Antibody (clone Bcl-2/100, FITC) IHC-plus™ LS-B4769
Mouse Monoclonal [clone Bcl-2/100] (IgG1) to Human BCL2 / Bcl-2
Human
Flo IHC IHC-P
FITC Conjugated
60tst  $485.00
Anti-BCL2 / Bcl-2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-BCL2 / Bcl-2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.

BCL2 / Bcl-2 Antibody (aa41-54) LS-C148227
Rabbit Polyclonal to Human BCL2 / Bcl-2
Dog, Pig, Human, Monkey
IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $335.00
Western blot of Bcl-2 using Polyclonal Antibody to Bcl-2 at 1:2000.20 ug/protein was loaded per lane. Lane 1. Human Jurkat T cells. Lane 2. Human RS11 lymphoma cells. Lanes 3-6. Human breast cancer cases. Patient sample in lane 5 lacked detectible Bcl-2 expression.

BCL2 / Bcl-2 Antibody (clone 10C4) LS-C107070
Mouse Monoclonal [clone 10C4] (IgG1,k) to Mouse BCL2 / Bcl-2
Mouse
Flo IP WB
Unconjugated
50µg  $245.00; 100µg 0.5mg/ml  $295.00

BCL2 / Bcl-2 Antibody (clone 11C5) IHC-plus™ LS-B7085
Mouse Monoclonal [clone 11C5] (IgG2a,k) to Human BCL2 / Bcl-2
Human
ELISA IHC IHC-P IP WB
Unconjugated
50µl  $425.00
Anti-BCL2 / Bcl-2 antibody IHC of human colon, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot Image

BCL2 / Bcl-2 Antibody LS-C26455
Sheep Polyclonal to Dog BCL2 / Bcl-2
Dog, Rat, Human
IF IP WB
Unconjugated
250µg 1mg/ml  $365.00

BCL2 / Bcl-2 Antibody (clone 8E+12) LS-C758627
Mouse Monoclonal [clone 8E+12] (IgG1) to Human BCL2 / Bcl-2
Mouse, Human
Flo ICC IF IHC
Unconjugated
100µl  $405.00
Bcl-2 Antibody in Immunohistochemistry (IHC)
Bcl-2 Antibody in Immunofluorescence (IF)
Showing 1-25 of 298 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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