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ACE / CD143

angiotensin I converting enzyme

ACE / CD143 is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Gene Name: angiotensin I converting enzyme
Family/Subfamily: Protease , Metallopeptidase M2
Synonyms: ACE, ACE1, Angiotensin-converting enzyme, CD143, CD143 antigen, Carboxycathepsin, DIPEPTIDYL CARBOXYPEPTIDASE, DCP, Dipeptidyl carboxypeptidase I, ICH, Kininase II, MVCD3, Peptidyl-dipeptidase A, Peptidase P, DCP1, Dipeptidyl carboxypeptidase 1, Testicular ECA
Target Sequences: NM_000789 NP_000780.1 P12821

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Products
Antibodies (119)
Primary (119)
ACE / CD143 (119)
Human (82)
Mouse (51)
Rat (26)
Bovine (5)
Cat (11)
Dog (2)
Guinea pig (1)
Hamster (10)
Monkey (18)
Orangutan (1)
Pig (9)
Rabbit (2)
Sheep (1)
IHC (46)
IHC-Fr (6)
IHC-P (10)
WB (91)
Flo (9)
ELISA (37)
ICC (23)
IP (22)
Neut (1)
Peptide-ELISA (1)
rabbit (75)
mouse (42)
goat (2)
Product Group
IHCPlus (1)
PathPlus Neuro (2)
IgG (18)
IgG1 (34)
IgG1,k (1)
IgG2a (2)
IgM (2)
monoclonal mc (42)
polyclonal pc (77)
2E2 (1)
3H7E4 (1)
6A4 (1)
CG2 (1)
I2H5 (2)
OTI2C8 (1)
OTI2G5 (1)
AP Conjugated (3)
APC (6)
APC Conjugated (9)
Biotin Conjugated (13)
Cy3 Conjugated (6)
Cy7 Conjugated (6)
FITC Conjugated (12)
HRP Conjugated (9)
PE Conjugated (11)
Unconjugated (50)
aa504-597 (16)
aa334-409 (10)
aa1160-1306 (8)
aa814-1071 (8)
aa918-1088 (8)
N-Terminus (6)
Internal (2)
aa1274-1306 (2)
aa30-1261 (2)
aa642-1230 (2)
C-Terminus (1)
Phe940 (1)
aa130-144 (1)
aa401-761 (1)
aa651-864 (1)
aa702-715 (1)
aa891-940 (1)
No (119)
ACE / CD143 Antibody - Anti-ACE antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Neuroscience
ACE / CD143 Mouse anti-Human Monoclonal Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Cat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$485
ACE / CD143 Antibody - Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Neuroscience
ACE / CD143 Mouse anti-Human Monoclonal (aa1274-1306) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
0.05 ml/$440
ACE / CD143 Antibody - Immunohistochemical analysis of CD143 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ACE / CD143 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$289
ACE / CD143 Antibody - Western blot of ACE1 antibody
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ACE / CD143 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µl/$277; 100 µl/$308; 200 µl/$374
ACE / CD143 Antibody - IHC: Mouse anti-Angiotensin-converting Enzyme (ANGIOTENSIN CONVERT ENZ,MSX-100UG) staining of rat heart myocardium three weeks after a myocardial infarction.
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ACE / CD143 Mouse anti-Human Monoclonal Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$637
ACE / CD143 Antibody - ACE antibody IHC-paraffin: Human Placenta Tissue.
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ACE / CD143 Rabbit anti-Human Polyclonal (aa651-864) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$397
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ACE / CD143 Mouse anti-Human Monoclonal (N-Terminus) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$739
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ACE / CD143 Mouse anti-Human Monoclonal (HRP) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IP, WB
HRP Conjugated
100 µl/$846
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ACE / CD143 Mouse anti-Human Monoclonal (Biotin) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IP, WB
Biotin Conjugated
100 µl/$846
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ACE / CD143 Mouse anti-Human Monoclonal (FITC) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IP, WB
FITC Conjugated
100 µl/$846
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ACE / CD143 Mouse anti-Human Monoclonal (AP) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IP, WB
AP Conjugated
100 µl/$846
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ACE / CD143 Mouse anti-Human Monoclonal (APC) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IP, WB
APC Conjugated
100 µl/$846
Select
ACE / CD143 Mouse anti-Human Monoclonal (PE) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, ICC, IHC, IP, WB
PE Conjugated
100 µl/$846
Select
ACE / CD143 Mouse anti-Human Monoclonal (N-Terminus) Antibody
Rat, Hamster, Cat, Human, Monkey
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
1 ml/$958
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ACE / CD143 Mouse anti-Human Monoclonal (N-Terminus) Antibody
Human
ELISA, ICC, IHC, IHC-Fr, IP
Unconjugated
100 µg/$711
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ACE / CD143 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, ICC, IHC, IP
Biotin Conjugated
100 µl/$836
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ACE / CD143 Mouse anti-Human Monoclonal (AP) Antibody
Human
ELISA, ICC, IHC, IP
AP Conjugated
100 µl/$836
Select
ACE / CD143 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, ICC, IHC, IP
APC Conjugated
100 µl/$836
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ACE / CD143 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, ICC, IHC, IP
PE Conjugated
100 µl/$836
ACE / CD143 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ACE / CD143 Rabbit anti-Human Polyclonal (aa814-1071) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
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ACE / CD143 Goat anti-Human Polyclonal (aa30-1261) Antibody
Human
ELISA, Flo, IHC, Neut, WB
Unconjugated
100 µg/$793
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ACE / CD143 Mouse anti-Human Monoclonal (Biotin) Antibody
Human, Monkey
ELISA, ICC, IHC, IP
Biotin Conjugated
100 µl/$813
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ACE / CD143 Mouse anti-Human Monoclonal (AP) Antibody
Human, Monkey
ELISA, ICC, IHC, IP
AP Conjugated
100 µl/$813
Select
ACE / CD143 Mouse anti-Human Monoclonal (APC) Antibody
Human, Monkey
ELISA, ICC, IHC, IP
APC Conjugated
100 µl/$813
Select
ACE / CD143 Mouse anti-Human Monoclonal (PE) Antibody
Human, Monkey
ELISA, ICC, IHC, IP
PE Conjugated
100 µl/$813
Viewing 1-25 of 119 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).