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Catalog Number Size Price
LS-B10663-0.05 0.05 ml $440 
ACE / CD143 Antibody - Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
ACE / CD143 Antibody - ACE Antibody (Ascites)western blot of mouse kidney tissue lysates (35 ug/lane). The ACE antibody detected the ACE protein (arrow).
ACE / CD143 Antibody - Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
ACE / CD143 Antibody - ACE Antibody (Ascites)western blot of mouse kidney tissue lysates (35 ug/lane). The ACE antibody detected the ACE protein (arrow).
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PathPlus™ Monoclonal Mouse anti‑Human ACE / CD143 Antibody (aa1274‑1306, IHC, WB) LS‑B10663

PathPlus™ Monoclonal Mouse anti‑Human ACE / CD143 Antibody (aa1274‑1306, IHC, WB) LS‑B10663

Note: This antibody replaces LS-C160996
Antibody:
ACE / CD143 Mouse anti-Human Monoclonal (aa1274-1306) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B10663-0.05
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ACE / CD143 Mouse anti-Human Monoclonal (aa1274-1306) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
ACE (Angiotensin-converting enzyme, CD143) is an enzyme involved in catalyzing the conversion of angiotensin I into the physiologically active angiotensin II. It has a central role in the renin-angiotensin system, which is involved in regulating blood pressure and fluid volume in the body. The 287 bp Alu repeat element in this gene is correlated with levels of circulating ACE enzyme and with cardiovascular patho-physiologies. Variants in ACE are also associated with Alzheimer’s disease, where deregulated levels of the protein have been found. In immunohistochemistry, ACE has positive staining in the lung capillary endothelium, basal ganglia neuropil, granulosa cells, Leydig cells, proximal renal tubule brush borders, the uterus, male genitalia, and endothelial cells of small or medium arteries. References: Am J Transl Res. 2011 Jan 1; 3(1): 73–80, PMID: 21139807; Alzheimers Res Ther. 2014; 6(3): 27, PMID: 24987467
Target
Human ACE / CD143
Synonyms
ACE | ACE1 | Angiotensin-converting enzyme | CD143 | CD143 antigen | Carboxycathepsin | DIPEPTIDYL CARBOXYPEPTIDASE | DCP | Dipeptidyl carboxypeptidase I | ICH | Kininase II | MVCD3 | Peptidyl-dipeptidase A | Peptidase P | DCP1 | Dipeptidyl carboxypeptidase 1 | Testicular ECA
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Epitope
aa1274-1306
Specificity
This ACE antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1274-1306 amino acids from human ACE.
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:16000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
0.09% Sodium Azide
Storage
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ACE / CD143
P12821 NM_000789 NP_000780.1

Validation

ACE / CD143 Antibody - Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

LSBio Ratings

PathPlus™ ACE / CD143 Antibody (aa1274-1306) for IHC, WB/Western LS-B10663 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/10/2024