Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B3265-50 50 µg (1 mg/ml) $495 
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
HGF / Hepatocyte Growth Factor Antibody - Western Blot: Lane 1- hHGF 1 ug, Lane 2- hHGF 0.5 ug, Lane 3- hHGF 0.25 ug.
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
HGF / Hepatocyte Growth Factor Antibody - Western Blot: Lane 1- hHGF 1 ug, Lane 2- hHGF 0.5 ug, Lane 3- hHGF 0.25 ug.
1 of 3
2 of 3
3 of 3

PathPlus™ Monoclonal Mouse anti‑Human HGF / Hepatocyte Growth Factor Antibody (clone 7‑2, IHC, WB) LS‑B3265

PathPlus™ Monoclonal Mouse anti‑Human HGF / Hepatocyte Growth Factor Antibody (clone 7‑2, IHC, WB) LS‑B3265

Note: This antibody replaces LS-C63073
Antibody:
HGF / Hepatocyte Growth Factor Mouse anti-Human Monoclonal (7-2) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$495
LS-B3265-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
HGF / Hepatocyte Growth Factor Mouse anti-Human Monoclonal (7-2) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
HGF (Hepatocyte growth factor, scatter factor) is a protein secreted by mesenchymal cells that functions in paracrine cell motility, growth and morphogenesis, as well as embryogenesis, organ regeneration and wound healing. It targets epithelial cells, endothelial cells, oligodendrocyte precursor cells, hameopoietic progenitor cells and T cells to induce migration as well as proliferative and angiogenic processes. Levels of expression of HGF are positively correlated with number of neocortical GABAergic interneurons and decreased HGF levels are associated with susceptibility to seizures -- increasing HGF levels has been shown to help lower susceptibility. HGF can activate Schwann cells to promote peripheral nerve regeneration. It is also thought to be involved in atherogenesis and is found in atherosclerotic plaques. In immunohistochemistry, HGF has moderate extracellular and cytoplasmic positivity in most tissues throughout the body. References: Biomed Res Int. 2013;2013:470418, PMID: 24490163; EXS. 1993;65:225-49, PMID: 8422545; Exp Cell Res. 2001 Jul 15;267(2):258-66, PMID: 11426944; Atherosclerosis. 2002 Sep;164(1):79-87; Atherosclerosis. 2002 Sep;164(1):79-87, PMID: 12119196; Scientific Reports. 2018. 8 (8316), DOI: 10.1038/s41598-018-26704-x; J Neurosci Res. 2002 Sep 1;69(5):597-606, PMID: 12210825;
Target
Human HGF / Hepatocyte Growth Factor
Synonyms
HGF | DFNB39 | Hepatocyte growth factor | Hepatopoeitin-A | Hepapoietin A | Hepatopoietin-A | Scatter factor) | SF | F-TCF | HGFB | HPTA | Scatter factor
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal
Clone
7-2
Conjugations
Unconjugated
Purification
Protein G purified from tissue culture supernatant
Modifications
Unmodified
Immunogen
Human HGF.
Specificity
Reacts with human HGF and to a lesser extent, mouse by Western Blot.
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: LS-B3265 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3265 was determined to be 10 ug/ml.
Presentation
PBS, 0.01% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HGF / Hepatocyte Growth Factor
P14210 X16323 CAA34387.1

Validation

HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-HGF antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-HGF antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-HGF antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-HGF antibody IHC of human brain, cerebellum, white matter. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

PathPlus™ HGF / Hepatocyte Growth Factor Antibody (clone 7-2) for IHC, WB/Western LS-B3265 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Expression of HGF, pMet, and pAkt is related to benefit of radiotherapy after breast-conserving surgery: a long-term follow-up of the SweBCG91-RT randomised trial. Martin Sjöström, Cynthia Veenstra, Erik Holmberg, Per Karlsson, Fredrika Killander, Per Malmström, Emma Niméus, Mårten Fernö, Olle Stål. Molecular oncology. 2020 September;

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 6/18/2024