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Catalog Number Size Price
LS-B4657-50 50 µl (0.5 mg/ml) $460 
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HGF / Hepatocyte Growth Factor Antibody - HGF antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HGF / Hepatocyte Growth Factor Antibody - HGF antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PathPlus™ Polyclonal Rabbit anti‑Human HGF / Hepatocyte Growth Factor Antibody (aa216‑265, IHC, WB) LS‑B4657

PathPlus™ Polyclonal Rabbit anti‑Human HGF / Hepatocyte Growth Factor Antibody (aa216‑265, IHC, WB) LS‑B4657

Note: This antibody replaces LS-C110933
Antibody:
HGF / Hepatocyte Growth Factor Rabbit anti-Human Polyclonal (aa216-265) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Rat
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-B4657-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
HGF / Hepatocyte Growth Factor Rabbit anti-Human Polyclonal (aa216-265) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Rat
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
HGF (Hepatocyte growth factor, scatter factor) is a protein secreted by mesenchymal cells that functions in paracrine cell motility, growth and morphogenesis, as well as embryogenesis, organ regeneration and wound healing. It targets epithelial cells, endothelial cells, oligodendrocyte precursor cells, hameopoietic progenitor cells and T cells to induce migration as well as proliferative and angiogenic processes. Levels of expression of HGF are positively correlated with number of neocortical GABAergic interneurons and decreased HGF levels are associated with susceptibility to seizures -- increasing HGF levels has been shown to help lower susceptibility. HGF can activate Schwann cells to promote peripheral nerve regeneration. It is also thought to be involved in atherogenesis and is found in atherosclerotic plaques. In immunohistochemistry, HGF has moderate extracellular and cytoplasmic positivity in most tissues throughout the body. References: Biomed Res Int. 2013;2013:470418, PMID: 24490163; EXS. 1993;65:225-49, PMID: 8422545; Exp Cell Res. 2001 Jul 15;267(2):258-66, PMID: 11426944; Atherosclerosis. 2002 Sep;164(1):79-87; Atherosclerosis. 2002 Sep;164(1):79-87, PMID: 12119196; Scientific Reports. 2018. 8 (8316), DOI: 10.1038/s41598-018-26704-x; J Neurosci Res. 2002 Sep 1;69(5):597-606, PMID: 12210825;
Target
Human HGF / Hepatocyte Growth Factor
Synonyms
HGF | DFNB39 | Hepatocyte growth factor | Hepatopoeitin-A | Hepapoietin A | Hepatopoietin-A | Scatter factor) | SF | F-TCF | HGFB | HPTA | Scatter factor
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide located between aa216-265 of human HGF (P14210, NP_000592). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Dog, Cat, Bovine, Rabbit, Horse, Pig, Opossum, Guinea pig (100%); Bat (92%); Turkey, Zebra finch, Chicken (85%).
Epitope
aa216-265
Specificity
Human HGF
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.2 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HGF / Hepatocyte Growth Factor
P14210 X16323 CAA34387.1

Validation

HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HGF antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HGF antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HGF antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-HGF antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

LSBio Ratings

PathPlus™ HGF / Hepatocyte Growth Factor Antibody (aa216-265) for IHC, WB/Western LS-B4657 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Novel MET/TIE2/VEGFR2 inhibitor altiratinib inhibits tumor growth and invasiveness in bevacizumab-resistant glioblastoma mouse models. Piao Y, Park SY, Henry V, Smith BD, Tiao N, Flynn DL, de Groot JF. Neuro-oncology. 2016 September;18:1230-41. (Human)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/27/2024