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Catalog Number Size Price
LS-B4957-200 200 µl $460 
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
HGF / Hepatocyte Growth Factor Antibody - The anti-HGF antibody is used in Western blot to detect HGF in Ramos tissue lysate. HGF (arrow) was detected using the purified antibody.
HGF / Hepatocyte Growth Factor Antibody - HGF Antibody flow cytometry of CEM cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
HGF / Hepatocyte Growth Factor Antibody - The anti-HGF antibody is used in Western blot to detect HGF in Ramos tissue lysate. HGF (arrow) was detected using the purified antibody.
HGF / Hepatocyte Growth Factor Antibody - HGF Antibody flow cytometry of CEM cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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PathPlus™ Polyclonal Rabbit anti‑Human HGF / Hepatocyte Growth Factor Antibody (aa521‑554, IHC, WB) LS‑B4957

PathPlus™ Polyclonal Rabbit anti‑Human HGF / Hepatocyte Growth Factor Antibody (aa521‑554, IHC, WB) LS‑B4957

Note: This antibody replaces LS-C97876
Antibody:
HGF / Hepatocyte Growth Factor Rabbit anti-Human Polyclonal (aa521-554) Antibody
Application:
IHC, IHC-P, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B4957-200
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
HGF / Hepatocyte Growth Factor Rabbit anti-Human Polyclonal (aa521-554) Antibody
Application:
IHC, IHC-P, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
HGF (Hepatocyte growth factor, scatter factor) is a protein secreted by mesenchymal cells that functions in paracrine cell motility, growth and morphogenesis, as well as embryogenesis, organ regeneration and wound healing. It targets epithelial cells, endothelial cells, oligodendrocyte precursor cells, hameopoietic progenitor cells and T cells to induce migration as well as proliferative and angiogenic processes. Levels of expression of HGF are positively correlated with number of neocortical GABAergic interneurons and decreased HGF levels are associated with susceptibility to seizures -- increasing HGF levels has been shown to help lower susceptibility. HGF can activate Schwann cells to promote peripheral nerve regeneration. It is also thought to be involved in atherogenesis and is found in atherosclerotic plaques. In immunohistochemistry, HGF has moderate extracellular and cytoplasmic positivity in most tissues throughout the body. References: Biomed Res Int. 2013;2013:470418, PMID: 24490163; EXS. 1993;65:225-49, PMID: 8422545; Exp Cell Res. 2001 Jul 15;267(2):258-66, PMID: 11426944; Atherosclerosis. 2002 Sep;164(1):79-87; Atherosclerosis. 2002 Sep;164(1):79-87, PMID: 12119196; Scientific Reports. 2018. 8 (8316), DOI: 10.1038/s41598-018-26704-x; J Neurosci Res. 2002 Sep 1;69(5):597-606, PMID: 12210825;
Target
Human HGF / Hepatocyte Growth Factor
Synonyms
HGF | DFNB39 | Hepatocyte growth factor | Hepatopoeitin-A | Hepapoietin A | Hepatopoietin-A | Scatter factor) | SF | F-TCF | HGFB | HPTA | Scatter factor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Epitope
aa521-554
Specificity
This HGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-554 amino acids from the C-terminal region of human HGF.
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.09% Sodium Azide
Storage
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HGF / Hepatocyte Growth Factor
P14210 X16323 CAA34387.1

Validation

HGF / Hepatocyte Growth Factor Antibody - Anti-HGF antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-HGF antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-HGF antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

LSBio Ratings

PathPlus™ HGF / Hepatocyte Growth Factor Antibody (aa521-554) for IHC, WB/Western, Flow LS-B4957 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (5)

Publications (1)

Expression of hypoxia-inducible factor-1 alpha and hepatocyte growth factor in development of fibrosis in the transplanted kidney. Kellenberger T, Marcussen N, Nyengaard JR, Wogensen L, Jespersen B. Transplant international : official journal of the European Society for Organ Transplantation. Feb;28:180-90.

Customer Reviews (0)


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Requested From: United States
Date Requested: 5/28/2024