Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B5932-50 50 µg (0.48 mg/ml) $460 
COL1A1 / Collagen I Alpha 1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
COL1A1 / Collagen I Alpha 1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
COL1A1 / Collagen I Alpha 1 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
COL1A1 / Collagen I Alpha 1 Antibody - COL1A1 monoclonal antibody clone 3G3. Western blot of COL1A1 expression in NIH/3T3.
COL1A1 / Collagen I Alpha 1 Antibody - Detection limit for recombinant GST tagged COL1A1 is 0.03 ng/ml as a capture antibody.
COL1A1 / Collagen I Alpha 1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
COL1A1 / Collagen I Alpha 1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
COL1A1 / Collagen I Alpha 1 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
COL1A1 / Collagen I Alpha 1 Antibody - COL1A1 monoclonal antibody clone 3G3. Western blot of COL1A1 expression in NIH/3T3.
COL1A1 / Collagen I Alpha 1 Antibody - Detection limit for recombinant GST tagged COL1A1 is 0.03 ng/ml as a capture antibody.
1 of 5
2 of 5
3 of 5
4 of 5
5 of 5

PathPlus™ Monoclonal Mouse anti‑Human COL1A1 / Collagen I Alpha 1 Antibody (clone 3G3, IHC, WB) LS‑B5932

PathPlus™ Monoclonal Mouse anti‑Human COL1A1 / Collagen I Alpha 1 Antibody (clone 3G3, IHC, WB) LS‑B5932

Note: This antibody replaces LS-C133871
Antibody:
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3G3) Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B5932-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3G3) Antibody
Application:
IHC-P, WB, ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
COL1A1 (Collagen I Alpha 1) is the pro-alpha1 chain of type I collagen, a fibril-forming collagen found in most connective tissues and abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. In immunohistochemistry, COL1A1 has cytoplasmic and extracellular positivity in all tissues throughout the body. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804;
Target
Human COL1A1 / Collagen I Alpha 1
Synonyms
COL1A1 | Alpha-1 type I collagen | Collagen alpha 1 chain type I | Collagen alpha-1(I) chain | Collagen, type I, alpha 1 | Collagen I | Pro-alpha-1 collagen type 1 | OI4
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG3,k Monoclonal
Clone
3G3
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
Amino acids 1021-1108 of NP_000079.1
Specificity
Human COL1A1
Applications
  • IHC - Paraffin (5 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using cell line lysates and the recombinant protein used as the immunogen.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About COL1A1 / Collagen I Alpha 1
P02452 NM_000088 NP_000079.2

Validation

COL1A1 / Collagen I Alpha 1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

COL1A1 / Collagen I Alpha 1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

COL1A1 / Collagen I Alpha 1 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ COL1A1 / Collagen I Alpha 1 Antibody (clone 3G3) for IHC, WB/Western, ELISA LS-B5932 has an LSBio Rating of
Publications (4.3)
Laboratory Validation Score (5)

Publications (4)

Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence. Petra Sántha, Daniela Lenggenhager, Anette Finstadsveen, Linda Dorg, Kristin Tøndel, Manoj Amrutkar, Ivar P Gladhaug, Caroline Verbeke. Cancers. 2021 February;13:

Mechanical process prior to cryopreservation of lipoaspirates maintains extracellular matrix integrity and cell viability: evaluation of the retention and regenerative potential of cryopreserved fat-derived product after fat grafting. Jingwei Feng, Wansheng Hu, Mimi Lalrimawii Fanai, Shengqian Zhu, Jing Wang, Junrong Cai, Feng Lu. Stem cell research & therapy. 2019 September;10:283.

In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization. Eirini Moysi, Perla M Del Rio Estrada, Fernanda Torres-Ruiz, Gustavo Reyes-Terán , Richard A Koup, Constantinos Petrovas. Frontiers in immunology. 2021 Jun;12:683396.

TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857.

more

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/23/2024