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COL1A1 / Collagen I Alpha 1

collagen, type I, alpha 1

COL1A1 / Collagen I Alpha 1 is the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Gene Name: collagen, type I, alpha 1
Family/Subfamily: Collagen , not assigned-Collagen
Synonyms: COL1A1, Alpha-1 type I collagen, Collagen alpha 1 chain type I, Collagen alpha-1(I) chain, Collagen, type I, alpha 1, Collagen I, Pro-alpha-1 collagen type 1, OI4
Target Sequences: NM_000088 NP_000079.2 P02452

Publications (7)

1
The Role of Periostin in Capsule Formation on Silicone Implants. Bae HS, Son HY, Lee JP, Chang H, Park JU. BioMed research international. 2018 April;2018:3167037. (Mouse, Human) [Full Text Article] [PubMed:29854742] [PMC:PMC5944282] Related Antibodies: LS-C343921.
2
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence. Petra Sántha, Daniela Lenggenhager, Anette Finstadsveen, Linda Dorg, Kristin Tøndel, Manoj Amrutkar, Ivar P Gladhaug, Caroline Verbeke. Cancers. 2021 February;13: [Full Text Article] [PubMed:33672734] [PMC:PMC7924365] Related Antibodies: LS-B5932.
3
Mechanical process prior to cryopreservation of lipoaspirates maintains extracellular matrix integrity and cell viability: evaluation of the retention and regenerative potential of cryopreserved fat-derived product after fat grafting. Jingwei Feng, Wansheng Hu, Mimi Lalrimawii Fanai, Shengqian Zhu, Jing Wang, Junrong Cai, Feng Lu. Stem cell research & therapy. 2019 September;10:283. [Full Text Article] [PubMed:31547884] [PMC:PMC6755707] Related Antibodies: LS-B5932.
4
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model. Min-Ha Choi , Jinhyun Kim , Jeong Hyun Ha, Ji-Ung Park. Scientific reports. 2021 March;11:5468. [Full Text Article] [PubMed:33750878] [PMC:PMC7943593] Related Antibodies: LS-C343921.
5
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article] [PubMed:31771627] [PMC:PMC6878650] Related Antibodies: LS-C343921.
6
BRCA1 mutation influences progesterone response in human benign mammary organoids. Zihui Zhang, Shuang Li, Jie Deng, Shaorong Yang, Ziwu Xiang, Hongyan Guo, Hongli Xi, Ming Sang, Wei Zhang. International journal of molecular medicine. 2019 May;45:1351-1360. [Full Text Article] [PubMed:32323728] [PMC:PMC7138280] Related Antibodies: LS-C343921.
7
In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization. Eirini Moysi, Perla M Del Rio Estrada, Fernanda Torres-Ruiz, Gustavo Reyes-Terán , Richard A Koup, Constantinos Petrovas. Frontiers in immunology. 2021 Jun;12:683396. [Full Text Article] [PubMed:34177929] [PMC:PMC8221112] Related Antibodies: LS-B5932.
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Antibodies (80)
Primary (80)
COL1A1 / Collagen I Alpha 1 (80)
Human (57)
Mouse (52)
Rat (23)
Bat (4)
Bovine (10)
Chicken (9)
Chimpanzee (6)
Cow (1)
Dog (9)
Gibbon (3)
Guinea pig (8)
Horse (4)
Monkey (8)
Pig (20)
Rabbit (5)
Sheep (1)
IHC (28)
IHC-Fr (2)
IHC-P (22)
WB (60)
Flo (1)
ELISA (17)
EM (1)
FLISA (1)
ICC (2)
IF (4)
IP (1)
RIA (4)
rabbit (69)
mouse (10)
goat (1)
Product Group
PathPlus Cancer (1)
IgG (19)
IgG2b,k (8)
IgG3,k (1)
monoclonal mc (10)
polyclonal pc (70)
3C3 (1)
3G3 (1)
AP Conjugated (1)
APC (4)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (11)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (10)
HRP Conjugated (8)
PE Conjugated (5)
Unconjugated (26)
aa1218-1440 (10)
aa1225-1453 (8)
aa1077-1106 (7)
aa253-471 (7)
aa1188-1237 (4)
aa1216-1265 (4)
C-Terminus (1)
aa1192-1207 (1)
No (78)
Yes (2)
COL1A1 / Collagen I Alpha 1 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3G3) Antibody
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$440
COL1A1 / Collagen I Alpha 1 Antibody - Collagen I antibody IHC-paraffin: Rat Lung Tissue.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1192-1207) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$421
COL1A1 / Collagen I Alpha 1 Antibody
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$438
COL1A1 / Collagen I Alpha 1 Antibody - Collagen Type I on chicken skin paraffin section DAB, hematoxylin
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Chicken Polyclonal Antibody
Chicken
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.1 ml/$503
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COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3C3) Antibody
Mouse, Rat, Human
IHC-P
Unconjugated
20 µl/$242; 60 µl/$284; 120 µl/$343; 200 µl/$451
COL1A1 / Collagen I Alpha 1 Antibody - Collagen Type I on bovine skin paraffin section DAB, hematoxylin
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Bovine Polyclonal Antibody
Sheep, Bovine, Pig, Cow, Human
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.1 ml/$488; 0.5 ml/$869
COL1A1 / Collagen I Alpha 1 Antibody - Collagen I was detected in paraffin-embedded sections of mouse lung tissues using rabbit anti- Collagen I Antigen Affinity purified polyclonal antibody
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
100 µg/$421
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1077-1106) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$653
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1077-1106) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$828
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1077-1106) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$828
COL1A1 / Collagen I Alpha 1 Antibody
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$531
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA, IHC, WB
Biotin Conjugated
50 µg/$284; 100 µg/$348
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
IHC, IHC-P
Biotin Conjugated
0.1 ml/$406
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (DY488) Antibody
Mouse
IHC, IHC-P
DY488 Conjugated
0.1 ml/$406
COL1A1 / Collagen I Alpha 1 Antibody - COL1A1 antibody Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1188-1237) Antibody
Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Human, Monkey
WB
Unconjugated
100 µl/$414
COL1A1 / Collagen I Alpha 1 Antibody - Western blot analysis of Collagen 1 alpha 1 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
WB
Unconjugated
100 µl/$289
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Rat Polyclonal (FITC) Antibody
Rat
ELISA, WB
FITC Conjugated
50 µg/$284; 100 µg/$348
COL1A1 / Collagen I Alpha 1 Antibody - Western blot of recombinant COL1A1 / Collagen I.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1225-1453) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$380; 200 µl/$460; 500 µl/$799; 1 ml/$870
COL1A1 / Collagen I Alpha 1 Antibody - COL1A1 antibody Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1216-1265) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$459
COL1A1 / Collagen I Alpha 1 Antibody - Western blot of COL1A1 / Collagen I Alpha 1 antibody.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1218-1440) (PE) Antibody
Pig, Human
WB
PE Conjugated
100 µl/$375; 200 µl/$452; 500 µl/$774; 1 ml/$859
COL1A1 / Collagen I Alpha 1 Antibody - Collagen Type I on paraffin section of human skin DAB, haematoxylin
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.5 ml/$887
COL1A1 / Collagen I Alpha 1 Antibody
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
100 µg/$531
COL1A1 / Collagen I Alpha 1 Antibody - Collagen Type I on rat skin paraffin section DAB, hematoxylin
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.5 ml/$887
COL1A1 / Collagen I Alpha 1 Antibody - Frozen chicken dermal tissue section was stained with Goat Anti-Type I Collagen-FITC followed by DAPI.
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COL1A1 / Collagen I Alpha 1 Goat Polyclonal (FITC) Antibody
ELISA, EM, FLISA, Flo, ICC, IHC-Fr, IHC-P, IP, WB
FITC Conjugated
0.2 mg/$513
COL1A1 / Collagen I Alpha 1 Antibody - Immunohistochemistry of paraffin-embedded human esophageal cancer using COL1A1 antibodyat dilution of 1:100 (40x lens).
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).