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COL1A1 / Collagen I Alpha 1

collagen, type I, alpha 1

COL1A1 / Collagen I Alpha 1 is the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Gene Name: collagen, type I, alpha 1
Family/Subfamily: Collagen , not assigned-Collagen
Synonyms: COL1A1, Alpha-1 type I collagen, Collagen alpha 1 chain type I, Collagen alpha-1(I) chain, Collagen, type I, alpha 1, Collagen I, Pro-alpha-1 collagen type 1, OI4
Target Sequences: NM_000088 NP_000079.2 P02452

Publications (9)

1
The Role of Periostin in Capsule Formation on Silicone Implants. Bae HS, Son HY, Lee JP, Chang H, Park JU. BioMed research international. 2018 April;2018:3167037. (Mouse, Human) [Full Text Article] [PubMed:29854742] [PMC:PMC5944282] Related Antibodies: LS-C343921.
2
Morphological Heterogeneity in Pancreatic Cancer Reflects Structural and Functional Divergence. Petra Sántha, Daniela Lenggenhager, Anette Finstadsveen, Linda Dorg, Kristin Tøndel, Manoj Amrutkar, Ivar P Gladhaug, Caroline Verbeke. Cancers. 2021 February;13: [Full Text Article] [PubMed:33672734] [PMC:PMC7924365] Related Antibodies: LS-B5932.
3
Mechanical process prior to cryopreservation of lipoaspirates maintains extracellular matrix integrity and cell viability: evaluation of the retention and regenerative potential of cryopreserved fat-derived product after fat grafting. Jingwei Feng, Wansheng Hu, Mimi Lalrimawii Fanai, Shengqian Zhu, Jing Wang, Junrong Cai, Feng Lu. Stem cell research & therapy. 2019 September;10:283. [Full Text Article] [PubMed:31547884] [PMC:PMC6755707] Related Antibodies: LS-B5932.
4
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model. Min-Ha Choi , Jinhyun Kim , Jeong Hyun Ha, Ji-Ung Park. Scientific reports. 2021 March;11:5468. [Full Text Article] [PubMed:33750878] [PMC:PMC7943593] Related Antibodies: LS-C343921.
5
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article] [PubMed:31771627] [PMC:PMC6878650] Related Antibodies: LS-C343921.
6
BRCA1 mutation influences progesterone response in human benign mammary organoids. Zihui Zhang, Shuang Li, Jie Deng, Shaorong Yang, Ziwu Xiang, Hongyan Guo, Hongli Xi, Ming Sang, Wei Zhang. International journal of molecular medicine. 2019 May;45:1351-1360. [Full Text Article] [PubMed:32323728] [PMC:PMC7138280] Related Antibodies: LS-C343921.
7
In Situ Characterization of Human Lymphoid Tissue Immune Cells by Multispectral Confocal Imaging and Quantitative Image Analysis; Implications for HIV Reservoir Characterization. Eirini Moysi, Perla M Del Rio Estrada, Fernanda Torres-Ruiz, Gustavo Reyes-Terán , Richard A Koup, Constantinos Petrovas. Frontiers in immunology. 2021 Jun;12:683396. [Full Text Article] [PubMed:34177929] [PMC:PMC8221112] Related Antibodies: LS-B5932.
8
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. [Full Text Article] [PubMed:33913810] [PMC:PMC8143797] Related Antibodies: LS-B5932.
9
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis. Kasparas Petkevicius, Henrik Palmgren, Matthew S Glover, Andrea Ahnmark, Anne-Christine Andréasson, Katja Madeyski-Bengtson, Hiroki Kawana, Erik L Allman, Delaney Kaper, Martin Uhrbom, Liselotte Andersson, Leif Aasehaug, Johan Forsström, Simonetta Wallin, Ingela Ahlstedt, Renata Leke, Daniel Karlsson, Hernán González-King, Lars Löfgren, Ralf Nilsson, Giovanni Pellegrini, Nozomu Kono, Junken Aoki, Sonja Hess, Grzegorz Sienski, Marc Pilon, Mohammad Bohlooly-Y, Marcello Maresca, Xiao-Rong Peng. Nature communications. 2022 October;13:6020. [Full Text Article] [PubMed:36241646] [PMC:PMC9568529] Related Antibodies: LS-C343921.
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COL1A1 / Collagen I Alpha 1 (110)
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COL1A1 / Collagen I Alpha 1 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3G3) Antibody
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$460
COL1A1 / Collagen I Alpha 1 Antibody - Collagen I antibody IHC-paraffin: Rat Lung Tissue.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1192-1207) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
COL1A1 / Collagen I Alpha 1 Antibody - Collagen Type I on chicken skin paraffin section DAB, hematoxylin
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Chicken Polyclonal Antibody
Chicken
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.1 ml/$532
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (aa1077-1106) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
COL1A1 / Collagen I Alpha 1 Antibody
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$469
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$768
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
COL1A1 / Collagen I Alpha 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
139.01 kDa
20 µg/$150
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$764
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
COL1A1 / Collagen I Alpha 1 Protein - Recombinant Collagen Type I Alpha 1 By SDS-PAGE
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E. coli
His, N-Terminal
28.0 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
COL1A1 / Collagen I Alpha 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$718
COL1A1 / Collagen I Alpha 1 Protein - Recombinant  Collagen Type I Alpha 1 By SDS-PAGE
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E. coli
His, N-Terminal
26.4 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
COL1A1 / Collagen I Alpha 1 Antibody - Frozen chicken dermal tissue section was stained with Goat Anti-Type I Collagen-FITC followed by DAPI.
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COL1A1 / Collagen I Alpha 1 Goat Polyclonal (FITC) Antibody
Chicken, Mouse, Rat, Human
ELISA, EM, FLISA, Flo, ICC, IHC-Fr, IHC-P, IP, WB
FITC Conjugated
0.2 mg/$554
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COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (3C3) Antibody
Mouse, Rat, Human
IHC-P
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
COL1A1 / Collagen I Alpha 1 Antibody - Western blot analysis of Collagen 1 alpha 1 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Human
WB
Unconjugated
100 µl/$299
COL1A1 / Collagen I Alpha 1 Antibody - Western blot of recombinant COL1A1 / Collagen I.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1225-1453) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$483; 200 µl/$599; 500 µl/$1,089; 1 ml/$1,297; 2 ml/$1,815; 5 ml/$3,403
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COL1A1 / Collagen I Alpha 1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
FITC Conjugated
100 µl/$363; 200 µl/$429; 500 µl/$672; 1 ml/$833; 2 ml/$1,076; 5 ml/$1,912
COL1A1 / Collagen I Alpha 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
COL1A1 / Collagen I Alpha 1 Antibody - Collagen Type I on bovine skin paraffin section DAB, hematoxylin
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Bovine Polyclonal Antibody
Sheep, Bovine, Pig, Cow, Human
ELISA, IF, IHC-P, RIA, WB
Unconjugated
0.1 ml/$498; 0.5 ml/$950
COL1A1 / Collagen I Alpha 1 Antibody - Collagen I was detected in paraffin-embedded sections of mouse lung tissues using rabbit anti- Collagen I Antigen Affinity purified polyclonal antibody
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COL1A1 / Collagen I Alpha 1 Rabbit anti-Mouse Polyclonal (aa1185-1207) Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 110 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).