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| Catalog Number | Size | Price |
|---|---|---|
| LS-A431-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human C5AR2 / GPR77 / C5L2 Antibody (Extracellular Domain, IHC) LS‑A431
PathPlus™ Polyclonal Rabbit anti‑Human C5AR2 / GPR77 / C5L2 Antibody (Extracellular Domain, IHC) LS‑A431
Antibody:
C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
Complement component 5a receptor 2 (C5AR2) is involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. Instead C5AR2 modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. C5AR2 may be involved in coronary artery disease and in the pathogenesis of sepsis.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human C5AR2 / GPR77 / C5L2
Synonyms
C5AR2 | G-protein coupled receptor 77 | GPF77 | GPR77 | C5L2 | G protein-coupled receptor 77
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from 2nd extracellular domain of human C5L2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Bovine, Pig (89%); Panda (84%).
Epitope
Extracellular Domain
Specificity
Human C5L2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (25 - 33 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About C5AR2 / GPR77 / C5L2
Validation
Brain, Glioblastoma
Brain, Glioblastoma
Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-C5L2 antibody IHC of human adrenal, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Brain, Amygdala
Brain, Amygdala
Brain, Alzheimer's disease, neurofibrillary tangle
Brain, Alzheimer's disease, neurofibrillary tangle
See More About...
LSBio Ratings
PathPlus™ C5AR2 / GPR77 / C5L2 Antibody (Extracellular Domain) for IHC LS-A431 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 10/31/2024
Date Requested: 10/31/2024
