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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LMNA / Lamin A+C Antibody LS‑C413010
Lamin A+C antibody LS-C413010 is an unconjugated mouse monoclonal antibody to human Lamin A+C (LMNA). Validated for IF and WB.
Catalog
Size
Price
LS-C413010-100
100 µl
Unavailable

Popular LMNA / Lamin A+C Products

Antibody
Species: Xenopus, Human, Mouse, Rat, Bovine
Applications: IHC, IHC - Frozen, Immunofluorescence, Western blot
Anti-Lamin A/C antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B119 dilution 1:100.
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Anti-Lamin A/C antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2005 dilution 1:50.
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Anti-Lamin A/C antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2973 dilution 1:100.
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Product Description

Lamin A+C antibody LS-C413010 is an unconjugated mouse monoclonal antibody to human Lamin A+C (LMNA). Validated for IF and WB.
About LMNA / Lamin A+C
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. P02545 NM_005572 NP_005563.1

LMNA Antibody, 70 kDa lamin Antibody, CDCD1 Antibody, CMD1A Antibody, EMD2 Antibody, FPLD Antibody, IDC Antibody, FPL Antibody, FPLD2 Antibody, Lamin A/C Antibody, Lamin Antibody, LFP Antibody, LMNC Antibody, LMN1 Antibody, LMNL1 Antibody, HGPS Antibody, Prelamin-A/C Antibody, PRO1 Antibody, Lamin A Antibody, Lamin A/C-like 1 Antibody, LGMD1B Antibody, CDDC Antibody, CMT2B1 Antibody, LDP1 Antibody


Specifications

Target
Human LMNA / Lamin A+C
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Monoclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Immunofluorescence (1:50 - 1:200)
  • Western blot (1:1000)
Immunogen
Purified recombinant human LMNA protein fragments expressed in E. coli.
Specificity
This antibody detects endogenous levels of Lamin A/C and does not cross-react with related proteins.
Presentation
0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.2% sodium azide, 50% glycerol.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Immunofluorescence

Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).
Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).

Western blot

Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).
Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).

Immunofluorescence

Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).
Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).

Western blot

Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).
Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).

Immunofluorescence

Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).
Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).

Western blot

Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).
Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).

Immunofluorescence

Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).
Immunofluorescent analysis of A549 cells fixed with 4% Paraformaldehyde and using anti-Lamin A/C mouse mAb (dilution 1:200).

Western blot

Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).
Western blot detection of Lamin A/C in MCF7,A549 and HeLa cell lysates using Lamin A/C mouse mAb (1:1000 diluted).

Requested From: 
Date Requested: 7/18/2018

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