LMNA / Lamin A+C

lamin A/C

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

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Products

Antibodies (153)

ELISA Kits (13)

Proteins (10)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (1)

Over-Expression Lysate (6)

Primary (153)

Recombinant (4)

Sandwich (9)

Target

LMNA / Lamin A+C (176)

Reactivity

Human (155)

Mouse (85)

Rat (77)

African green monkey (1)

Bovine (24)

Chicken (1)

Cynodon dactylon (4)

Dog (12)

Guinea pig (1)

Hamster (4)

Horse (3)

Monkey (5)

Pig (12)

Rabbit (3)

Sheep (4)

Xenopus (3)

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Application

IHC (61)

IHC-Fr (10)

IHC-P (25)

WB (144)

Flo (10)

ELISA (34)

ICC (46)

IF (39)

IP (31)

Peptide-ELISA (10)

Host

rabbit (92)

mouse (59)

goat (1)

chicken (1)

Product Group

IHCPlus (2)

PathPlus Neuro (3)

Isotype

IgG (60)

IgG1 (25)

IgG1,k (9)

IgG2 (1)

IgG2a (1)

IgG2b (2)

IgG3 (8)

IgG3,k (1)

IgM (1)

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Clonality

monoclonal mc (58)

polyclonal pc (95)

Clone

1073CT3.1.3 (1)

12A-2F5 (6)

131C3 (2)

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13A4D4 (1)

40000000 (1)

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Azide-free (1)

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Magnetic beads Conjugated (1)

PE Conjugated (6)

Preservative Free (1)

Sepharose Conjugated (1)

Unconjugated (104)

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Epitope

aa1-422 (8)

aa401-427 (7)

C-Terminus (6)

pSer392 (4)

Internal (3)

N-Terminus (3)

pSer22 (3)

330-410 aa (2)

Cleaved (2)

Cleaved-Asp230 (2)

aa249-266 (2)

aa598-611 (2)

1-80 aa (1)

150-230 aa, Internal (1)

180-260 aa, Internal (1)

Arg386 (1)

Asp230 (1)

Ser17 (1)

aa1-50 (1)

aa150-200 (1)

aa17-66 (1)

aa181-230 (1)

aa2-51 (1)

aa212-261 (1)

aa319-566 (1)

aa361-410 (1)

aa398-490 (1)

aa400-450 (1)

aa451-468 (1)

aa455-469 (1)

aa464-572 (1)

aa465-498 (1)

aa481-646 (1)

aa550-600 (1)

aa572-646 (1)

aa59-572 (1)

p22 (1)

p392 (1)

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Publications

No (174)

Yes (2)

Sample Type

Adherent Cell Cultures (3)

Cell Lysates (2)

Plasma (6)

Serum (6)

Tissue Homogenates (6)

Tag

GST (1)

His-T7 (1)

Myc-DDK (Flag) (8)

Species

Human (7)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (1)

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PathPlus™ LMNA / Lamin A+C Antibody (C-Terminus) LS-B2005

Neuroscience

(5.0) Rating

(2) Publication(s)

Antibody:

LMNA / Lamin A+C Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$440

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IHC-plus™ LMNA / Lamin A+C Antibody (aa249-266) LS-B119

(4.0) Rating

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (aa249-266) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Hamster, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

LMNA / Lamin A+C Antibody (aa59-572) LS-C186225

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (aa59-572) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

LMNA / Lamin A+C Antibody LS-C25073

(4.0) Rating

(1) Publication(s)

Antibody:

LMNA / Lamin A+C Mouse anti-Xenopus Monoclonal Antibody

Reactivity:

Xenopus, Rat, Mouse, Bovine, Human

Applications:

IF, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

50 µg/$891

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Human LMNA / Lamin A+C (Sandwich ELISA) ELISA Kit - LS-F7332

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Mouse LMNA / Lamin A+C (Sandwich ELISA) ELISA Kit - LS-F49466

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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PathPlus™ LMNA / Lamin A+C Antibody (aa464-572, clone JOL2) LS-B2973

Neuroscience

(5.0) Rating

Antibody:

LMNA / Lamin A+C Mouse anti-Human Monoclonal (aa464-572) (JOL2) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.05 ml/$485

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LMNA / Lamin A+C Antibody (Internal) LS-C352469

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Chicken, Rat, Pig, Mouse, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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LMNA / Lamin A+C Antibody (aa572-646, clone JOL4) LS-C82328

Antibody:

LMNA / Lamin A+C Mouse anti-Human Monoclonal (aa572-646) (JOL4) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

1 ml/$429

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PathPlus™ LMNA / Lamin A+C Antibody (clone 133A2) LS-B7178

Neuroscience

(5.0) Rating

Antibody:

LMNA / Lamin A+C Mouse anti-Human Monoclonal (133A2) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Human

Applications:

Flo, ICC, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$440

Select

Human LMNA / Lamin A+C (Sandwich ELISA) ELISA Kit - LS-F52192

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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LMNA / Lamin A+C Antibody LS-C204529

Antibody:

LMNA / Lamin A+C Chicken anti-Human Polyclonal Antibody

Reactivity:

Mouse, Bovine, Rat, Pig, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$376

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LMNA / Lamin A+C Antibody (C-Terminus, Sepharose) LS-C171858

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (C-Terminus) (Sepharose) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IP

Format:

Sepharose Conjugated

Price:

100 µg/$399

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LMNA / Lamin A+C Antibody (clone 131C3) LS-C146766

Antibody:

LMNA / Lamin A+C Mouse anti-Human Monoclonal (131C3) Antibody

Reactivity:

Mouse, Dog, Sheep, Bovine, Rat, Hamster, Human

Applications:

Flo, ICC, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

0.1 mg/$424

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LMNA / Lamin A+C Antibody (Internal) LS-C352468

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Bovine, Rat, Pig, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

LMNA / Lamin A+C Antibody (phospho-Ser392) LS-C354018

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (pSer392) Antibody

Reactivity:

Mouse, Bovine, Rat, Pig, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$315

Select

LMNA / Lamin A+C Antibody LS-C801542

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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LMNA / Lamin A+C Antibody (phospho-Ser392) LS-C800917

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (pSer392) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

IHC-plus™ LMNA / Lamin A+C Antibody (aa212-261) LS-B7729

(4.0) Rating

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (aa212-261) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

LMNA / Lamin A+C Antibody (aa481-646) LS-C357473

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (aa481-646) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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LMNA / Lamin A+C Antibody (aa598-611) LS-C25076

Antibody:

LMNA / Lamin A+C Mouse anti-Human Monoclonal (aa598-611) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Human

Applications:

Flo, ICC, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

100 µg/$658

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LMNA / Lamin A+C Antibody (p392) LS-C821858

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (p392) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

LMNA / Lamin A+C Antibody LS-C757223

Antibody:

LMNA / Lamin A+C Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

300 µg/$422

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LMNA / Lamin A+C Antibody LS-C417355

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

LMNA / Lamin A+C Antibody (phospho-Ser392) LS-C416438

Antibody:

LMNA / Lamin A+C Rabbit anti-Human Polyclonal (pSer392) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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