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Catalog Number Size Price
LS-B360-50 50 µl (85 mg/ml) $495 
Cullin 4A / CUL4A Antibody - Anti-CUL4A / Cullin 4A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.

IHC‑plus™ Polyclonal Rabbit anti‑Human Cullin 4A / CUL4A Antibody (aa1‑25, IHC, WB) LS‑B360

IHC‑plus™ Polyclonal Rabbit anti‑Human Cullin 4A / CUL4A Antibody (aa1‑25, IHC, WB) LS‑B360

Note: This antibody replaces LS-C19048
Antibody:
Cullin 4A / CUL4A Rabbit anti-Human Polyclonal (aa1-25) Antibody
Application:
IHC, IHC-P, WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$495
LS-B360-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
Cullin 4A / CUL4A Rabbit anti-Human Polyclonal (aa1-25) Antibody
Application:
IHC, IHC-P, WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
CUL4A antibody LS-B360 is an unconjugated rabbit polyclonal antibody to human CUL4A (Cullin 4A) (aa1-25). Validated for ELISA, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human Cullin 4A / CUL4A
Synonyms
CUL4A | CUL-4A | Cullin-4A | Cullin 4A
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Delipidated and defibrinated followed by sterile filtration
Modifications
Unmodified
Immunogen
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N-Terminal region near amino acids 1-25 of Human Cul4A coupled to KLH.
Epitope
aa1-25
Specificity
Reacts with human Cullin 4A. Cross reactivity is expected against mouse Cul4A based on a high degree of sequence homology. Cross reactivity with other human cullins may occur.
Applications
  • IHC
  • IHC - Paraffin (1:500)
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation (1:500)
  • ELISA (1:2000 - 1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistochemistry: LS-B360 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B360 was determined to be 1:500.
Presentation
Antiserum, 0.01% Sodium Azide
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About Cullin 4A / CUL4A
Q13619 NM_003589 NP_003580.1

Validation

Cullin 4A / CUL4A Antibody - Anti-CUL4A / Cullin 4A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
Anti-CUL4A / Cullin 4A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
Anti-CUL4A / Cullin 4A antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.

LSBio Ratings

IHC-plus™ Cullin 4A / CUL4A Antibody (aa1-25) for IHC, WB/Western, IP, ELISA LS-B360 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)

Publications (3)

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM. Cell. 1996 85:829-39.

Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. Higa LA, Mihaylov IS, Banks DP, Zheng J, Zhang H. Nature cell biology. 2003 5:1008-15.

Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma. Mayura Meerang, Jessica Kreienbühl, Vanessa Orlowski, Seraina L C Müller, Michaela B Kirschner, Isabelle Opitz. Cancers. 2020 November;12:

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 2/28/2024