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Anti-TP53 / p53 Antibody (aa10-16, clone DO-2) LS-C11555

Note: This antibody replaces LS-C43563

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TP53 / p53 Antibodies

Anti-TP53 / p53 Antibody (clone BP53-12) IHC-plus™ LS-B431
Mouse Monoclonal [clone BP53-12] (IgG2a,k) to Human TP53 / p53
Human
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TP53 / p53 Antibody (clone PAb240, Azide-free) LS-C87442
Mouse Monoclonal [clone PAb240] (IgG1) to Mouse TP53 / p53
Mouse, Human
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated, Azide-free
Immunohistochemistry Image
Anti-TP53 / p53 Antibody (clone 6F2D3) LS-C203312
Mouse Monoclonal [clone 6F2D3] (IgG1) to Human TP53 / p53
Human
Western blot, Flow Cytometry, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone DO-2] (IgG1) to Human TP53 / p53
Human
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Human TP53 / p53
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [DO-2]
Unconjugated
Purified IgG
Unmodified

Applications

  • IHC - Paraffin (1:1000)
  • IHC - Frozen
  • Western blot (1:1000)
  • Immunoprecipitation

Specificity and Use

TP53 / p53 antibody was raised against recombinant human p53 ( AA 10-16 ).
aa10-16
Recognizes the human p53 tumor suppressor protein, also known as cellular tumor antigen p53 or NY-CO-13. Clone DO-1 binds to both wild type and mutant forms of the p53 protein found in various malignancies. p53 is important in multicellular organisms, where it regulates cell cycle progression to allow DNA repair or apoptosis in the case of irreparably damaged cells and thus functions as a tumor suppressor that is involved in preventing cancer. Mutations in the p53 gene are found in about half the cases of human cancerrecognizes an epitope at the N-terminal end of p53 between amino acids 20-25, common to isoforms 1-3 of p53.
Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium Citrate buffer pH 6.0 is recommended for this purpose.

Packaging

PBS, pH 7.4, 0.09% sodium azide.
For research use only.

About TP53 / p53

P04637 NM_000546 NP_000537.3

TP53 Antibody, BCC7 Antibody, Cellular tumor antigen p53 Antibody, p53 Antibody, TRP53 Antibody, p53 tumor suppressor Antibody, Phosphoprotein p53 Antibody, Antigen NY-CO-13 Antibody, Tumor protein p53 Antibody, Tumor suppressor p53 Antibody, LFS1 Antibody

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases.

Requested From: United States
Date Requested: 12/4/2016

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