Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Goat Polyclonal to Human SOD2 / Mn SOD
Human SOD2 / Mn SOD
Human, Rat (tested or 100% immunogen sequence identity)
Specificity and Use
SOD2 / Mn SOD antibody was raised against a synthetic peptide, which represented a portion of human manganese superoxide dismutase encoded within exon 5 (LocusLink ID 6648).
Specific for MnSOD. Recognizes rat MnSOD. Other species have not been tested. Reactivity with human is expected owing to the use of a peptide that corresponds to human MnSOD for antibody production. Reactivity with mouse is likely due to the conservation
Suitable for use in Western Blot.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
MNSOD / SOD2 is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.