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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B3161-50 50 µl (1 mg/ml) $425 
SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
SOD2 / Mn SOD Antibody
SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
SOD2 / Mn SOD Antibody
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PathPlus™ Monoclonal Mouse anti‑Human SOD2 / Mn SOD Antibody (IHC, WB) LS‑B3161

PathPlus™ Monoclonal Mouse anti‑Human SOD2 / Mn SOD Antibody (IHC, WB) LS‑B3161

Note: This antibody replaces LS-C61911
Antibody:
Mouse Monoclonal to Human SOD2 / Mn SOD
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B3161-50
50 µl
1 mg/ml
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Mouse Monoclonal to Human SOD2 / Mn SOD
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
SOD2 (superoxide dismutase 2, mitochondrial, MnSOD ) is a mitochondrial protein that converts toxic superoxide byproducts and to diatomic oxygen and hydrogen peroxide. It functions to clear reactive oxygen species in the mitochondria and thus it plays an important role in protecting against apoptosis, cell death and oxidative stress. Mutations in SOD2 may lead to a number of diseases including idiopathic cardiomyopathy, cancer, premature aging syndromes, and neurodegenerative diseases including Alzheimer’s, Parkinson’s, and sporadic motor neuron disease. In immunohistochemistry, SOD2 has granular cytoplasmic positivity in all tissues. References: J Bio Chem. 278 (15): 13294–301. doi:10.1074/jbc.M208670200, PMID: 12551919; Biochemistry. 48 (15): 3417–24. doi:10.1021/bi8023288, PMID: 19265433; Free Radic Biol Med. 2013 Sep;62:4-12, PMID: 23727323
Target
Human SOD2 / Mn SOD
Synonyms
SOD2 | IPOB | MVCD6 | Indophenoloxidase B | Mn superoxide dismutase | MNSOD | Mangano-superoxide dismutase
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50)
  • Western blot (1:2000)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant human SOD2 purified from E. coli.
Usage
Immunohistochemistry: LS-B3161 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3161 was determined to be 1:50.
Presentation
HEPES, 0.15 M NaCl, 0.03% Sodium Azide, 50% Glycerol, 0.01% BSA
Storage
Store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SOD2 / Mn SOD
P04179 NM_000636 NP_000627.2

Validation

SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-SOD2 / MNSOD antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-SOD2 / MNSOD antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-SOD2 / MNSOD antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-SOD2 / MNSOD antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

SOD2 / Mn SOD Antibody - Anti-SOD2 / MNSOD antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-SOD2 / MNSOD antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-SOD2 / MNSOD antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

LSBio Ratings

PathPlus™ SOD2 / Mn SOD Antibody for IHC, WB/Western, ELISA LS-B3161 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 7/5/2020