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Anti-Proenkephalin / PENK Antibody (C-Terminus) LS-C23074


Wt. Vol. Conc. Price
- 100 µl - Unavailable

Most Popular Proenkephalin / PENK Antibodies

Anti-Proenkephalin / PENK Antibody (N-Terminus) LS-C23082
Rabbit Polyclonal (IgG) to Human Proenkephalin / PENK
Human, Mouse, Rat
Anti-Proenkephalin / PENK Antibody LS-C23084
Rabbit Polyclonal to Rat Proenkephalin / PENK
Rat, Human, Mouse, Bovine, Dog, Guinea pig, Horse
IHC - Frozen
Anti-Proenkephalin / PENK Antibody (aa84-94) LS-C87228
Goat Polyclonal to Mouse Proenkephalin / PENK
Mouse, Rat

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG) to Rat Proenkephalin / PENK
Rat, Guinea pig, Hamster, Rabbit
IHC - Frozen, ICC


Rat Proenkephalin / PENK
Rat, Guinea pig, Hamster, Rabbit (tested or 100% immunogen sequence identity)
IgG Monoclonal
Tissue culture supernatant


  • IHC - Frozen
  • ICC (1:150)

Specificity and Use

Proenkephalin / PENK antibody was raised against leu5-enkephalin conjugated to BSA.
Recognizes rat Met5-and Leu5-enkephalin. Displays about 40% cross-reactivity with C-terminal extended Met-enkephalin hexapeptides and 7% cross-reactivity with the extended heptapeptide (-Arg-Phe-OH) but does not recognize other endogenous peptides. By IHC no cross-reactivity to beta-endorphin or dynorphin. Species cross-reactivity: guinea pig, hamster and rabbit.
Suitable for use in Immunohistochemistry and Immunocytochemistry. Immunohistochemistry: 1:50-1:200. Cryostat sections of rat and guinea pig brain stems. Immunocytochemistry: 1:150 primary cultures of rat striatal and hippocampal neurons using Cy2 or Cy3 conjugated secondary antibody for detection.


Diluted serum in PBS, 0.1% Thimerosal.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About Proenkephalin / PENK

P01210 NM_006211 NP_006202.1

PENK Antibody, Enkephalin A Antibody, Met enkephalin Antibody, Preproenkephalin Antibody, Proenkephalin Antibody, Proenkephalin-A Antibody

Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.

Requested From: 
Date Requested: 3/29/2017

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