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Anti-NCSTN / Nicastrin Antibody (Internal) IHC-plus™ LS-B1380

Note: This antibody replaces LS-C19655, LS-C42515


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular NCSTN / Nicastrin Antibodies

Anti-NCSTN / Nicastrin Antibody (C-Terminus) IHC-plus™ LS-B530
Rabbit Polyclonal to Human NCSTN / Nicastrin
Human, Mouse, Rat
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-NCSTN / Nicastrin Antibody (clone AT3B2) IHC-plus™ LS-B3583
Mouse Monoclonal [clone AT3B2] (IgG2b,k) to Human NCSTN / Nicastrin
Human, Mouse
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NCSTN / Nicastrin
Human, Mouse, Rat
IHC - Paraffin, Western blot


Human NCSTN / Nicastrin
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.5 - 1 µg/ml)

Specificity and Use

NCSTN / Nicastrin antibody was raised against synthetic peptide from human NCSTN / Nicastrin.
LS-E30289 - Liquid - 50 µg - $145.00
18 amino acid peptide from near the center of human Nicastrin
Immunohistochemistry: LS-B1380 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1380 was determined to be 5 ug/ml.


PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About NCSTN / Nicastrin

Q92542 NM_015331 NP_056146.1

NCSTN Antibody, Anterior pharynx-defective 2 Antibody, ATAG1874 Antibody, KIAA0253 Antibody, Nicastrin Antibody, APH2 Antibody, RP11-517F10.1 Antibody

NCSTN / Nicastrin is a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly.


Anti-NCSTN / Nicastrin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1380 concentration 5 ug/ml.


Immunofluorescence of Nicastrin in Human Brain cells with Nicastrin antibody at 20 ug/ml.

Western blot

Western blot
Western blot of Nicastrin in human brain tissue lysate with Nicastrin antibody at (A) 0.5 and (B) 1ug/ml.

Requested From: United States
Date Requested: 10/22/2016

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