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Anti-ITGA6/Integrin Alpha 6/CD49f Antibody (Biotin) LS-C45278

Note: This antibody replaces LS-C58620

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $345
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ITGA6/Integrin Alpha 6/CD49f Antibodies

Anti-ITGA6/Integrin Alpha 6/CD49f Antibody (Internal) IHC-plus™ LS-A8768
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGA6/Integrin Alpha 6/CD49f Antibody (N-Terminus) IHC-plus™ LS-A8770
Rabbit Polyclonal to Human ITGA6/Integrin Alpha 6/CD49f
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-ITGA6/Integrin Alpha 6/CD49f Antibody IHC-plus™ LS-B11070
Mouse Monoclonal (IgG1) to Human ITGA6/Integrin Alpha 6/CD49f
Human
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2a) to Human ITGA6/Integrin Alpha 6/CD49f
Human, Mouse, Dog, Pig, Sheep, Cynomolgus monkey
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human ITGA6/Integrin Alpha 6/CD49f
Rat
Human, Mouse, Dog, Pig, Sheep, Cynomolgus monkey (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Biotin. Also available Unconjugated or conjugated with FITC, RPE.
Protein G purified
Unmodified

Applications

  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:5)
  • (applications tested for the base form of this product only)

Specificity and Use

ITGA6/Integrin Alpha 6/CD49f antibody was raised against bALB/c mouse mammary tumor cells.
Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). In immunohistology the monoclonal Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 platelets in 100 ul. Method sheets are available on request.

Packaging

PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
For research use only.

About ITGA6/Integrin Alpha 6/CD49f

P23229 NM_000210 NP_000201.2

ITGA6 Antibody, CD49f Antibody, CD49f antigen Antibody, Integrin alpha6B Antibody, Integrin, alpha 6 Antibody, Integrin alpha-6 precursor Antibody, VLA-6 Antibody, Integrin alpha-6 Antibody, ITGA6B Antibody

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Requested From: United States
Date Requested: 12/3/2016

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