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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GSK3A / GSK3 Alpha Antibody (phospho‑Ser21) LS‑C36506
Antibody
GSK3 Alpha antibody LS-C36506 is an unconjugated rabbit polyclonal antibody to GSK3 Alpha (GSK3A) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C36506-100
100 µg
Unavailable

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Product Description

GSK3 Alpha antibody LS-C36506 is an unconjugated rabbit polyclonal antibody to GSK3 Alpha (GSK3A) from human, mouse and rat. Validated for WB.
About GSK3A / GSK3 Alpha
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. P49840 NM_019884 NP_063937.2

GSK3A Antibody, GSK-3 alpha Antibody, GSK3 alpha Antibody


Specifications

Target
Human GSK3A / GSK3 Alpha
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
Phosphopeptide containing S21 site of GSK-3a.
Epitope
pSer21
Specificity
Detects endogenous 51kD human, mouse, and rat GSK-3a phosphorylated at S21 using Western Blot. Does not detect phosphorylated GSK-3b.
Usage
Western Blot: An antibody concentration of 1.0 ug/ml is recommended.
Presentation
Lyophilized.
Reconstitution
100 µl deionized water
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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