Drosophila GSK3A / GSK3 Alpha
GSK3A | GSK-3 alpha | GSK3 alpha
(tested or 100% immunogen sequence identity)
Also available conjugated with AP
Synthetic peptide (aa203-219, C-KQLLHGEPNVS[ pY]ICSRY) corresponding to the catalytic domain (between subdomain VII & VIII) of Drosophila GSK-3/shaggy enzyme coupled to ovalbumin. Percent identity by BLAST analysis: Drosophila, Mosquito (100%); Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus, Xenopus, Stickleback, Pufferfish, Zebrafish (82%).
Recognizes Drosophila Glycogen Synthase Kinase 3, phosphorylated (Y279/Y216) (phosphoGSK-3)-Y216 for drosophila, Y279 for human. Species cross-reactivity: Mouse, rat, human, S. pombe and Dictyostelium. Expected to cross-react with nearly all species because of the extremely high conservation of this region among the known enzymes of many different species.