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Anti-ESPL1 / Separase Antibody (C-Terminus, clone XJ11-1B12, DY488) LS-C141151

Ordering

Wt. Vol. Conc. Price
- 100 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular ESPL1 / Separase Antibodies

Anti-ESPL1 / Separase Antibody (clone 6H6) IHC-plus™ LS-B6199
Mouse Monoclonal [clone 6H6] (IgG2a,k) to Human ESPL1 / Separase
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-ESPL1 / Separase Antibody (aa767-816) IHC-plus™ LS-B8366
Rabbit Polyclonal (IgG) to Human ESPL1 / Separase
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone XJ11-1B12] (IgG1,k) to Human ESPL1 / Separase
Human
Immunofluorescence, Western blot (applications tested for the base form of this product only)
DY488 Conjugated

Details

Human ESPL1 / Separase
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [XJ11-1B12]
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Protein G purified
Unmodified

Applications

  • Immunofluorescence
  • Western blot (1:500)
  • (applications tested for the base form of this product only)

Specificity and Use

ESPL1 / Separase antibody was raised against maltose-Binding Protein fusion of a C-terminal fragment of human Separase (residues 1866-1996)
C-Terminus
Separase (XJ11-1B12).
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

50 mM sodium borate
Store at 4°C. Do not freeze.
For research use only.

About ESPL1 / Separase

Q14674 NM_012291 NP_036423.4

ESPL1 Antibody, ESP1 Antibody, Extra spindle poles like 1 Antibody, KIAA0165 Antibody, Caspase-like protein ESPL1 Antibody, SEPA Antibody, Separase Antibody, Separin Antibody

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex.

Western blot

Western blot
Separase detected in 5C6 cell lysates. Lane 1: Non-induced lysate. Lane 2: Lysate induced with ponasterone. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Separase detected in 5C6 cell lysates using LS-C2890. Lane 1: non-induced lysate, Lane 2: Lysate induced with ponasterone. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/7/2016

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