Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
EP300 Antibody, E1A binding protein p300 Antibody, Histone acetyltransferase p300 Antibody, KAT3B Antibody, p300 HAT Antibody, E1A-associated protein p300 Antibody, E1A-binding protein, 300kD Antibody, p300 Antibody, RSTS2 Antibody
Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein.
Detection of p300 in varying amounts of whole cell lysates from HeLa cells, as indicated in A. with Rabbit anti-Human p300 (LS-C45675). Immunoprecipitation of a nuclear extract (NE) or a cytosolic (S100) extract from HeLa cells with 20 ug/10 mg lysate with LS-C45675 followed by resolving of immunoprecipitate by SDS page and Coomassie staining. Identity of p300 band was confirmed by mass spectroscopy.
Requested From: United States
Date Requested: 2/19/2017