Target
Human BDNF
Synonyms
BDNF | ANON2 | Abrineurin | BULN2 | Neurotrophin
Reactivity
Human, Mouse, Rat, Xenopus
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Immunogen
Synthetic peptide from the N-Terminus of human BDNF (HSDPARRGELSVCDSISEWV, aa129-148 of UniProt P23560). Percent identity by BLAST analysis: Mouse, Xenopus (100%).
Applications
- Western blot (0.5 - 1 µg/ml)
Usage
Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields. BDNF has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee