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Catalog Number Size Price
LS-B11849-50 50 µl $460 
BDNF Antibody - Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
BDNF Antibody - Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
BDNF Antibody - Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
BDNF Antibody - Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PathPlus™ Polyclonal Chicken anti‑Mouse BDNF Antibody (IHC, WB) LS‑B11849

PathPlus™ Polyclonal Chicken anti‑Mouse BDNF Antibody (IHC, WB) LS‑B11849

Note: This antibody replaces LS-C152848
Antibody:
BDNF Chicken anti-Mouse Polyclonal Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, IP
Reactivity:
Mouse, Human, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B11849-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
BDNF Chicken anti-Mouse Polyclonal Antibody
Application:
IHC, IHC-P, IHC-Fr, WB, IP
Reactivity:
Mouse, Human, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
BDNF (Brain-derived neurotrophic factor, ANON2) is a neurotrophin family growth factor that is expressed in the nervous system. It promotes neuronal survival and differentiation in the peripheral and central nervous systems during development. It plays an important role in axonal growth, pathfinding and in regulating dendritic morphology and growth. BDNF has a wide range of functions in adaptive neuronal responses, and it regulates synaptic transmission and plasticity at adult synapses in many regions of the CNS. It is also required for specific types of hippocampal-dependent memory and information storage. In immunohistochemistry, BDNF has cytoplasmic positivity in the hippocampus, cortex, and basal forebrain, and it is found throughout the nervous system as well as in the retina, kidney, prostate, motor neurons and skeletal muscle. References: Hippocampus. 2016 Jun;26(6):739-51, PMID: 26662461; Archives of Oral Biology. 54 (7): 689–95, PMID: 19467646; Frontiers in Neurology. 2018. 9, PMC: 6117390.
Target
Mouse BDNF
Synonyms
BDNF | ANON2 | Abrineurin | BULN2 | Neurotrophin
Host
Chicken
Reactivity
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgY Polyclonal
Conjugations
Unconjugated
Purification
PEG purified
Modifications
Unmodified
Immunogen
Fusion protein from mouse proBDNF containing only the prodomain region
Specificity
Reacts with proBDNF. Does not recognize mature BDNF isoforms
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • IHC - Frozen
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western blot: 1:500-1:1000. Reacts with bands of 30 kD and 28 kD. Immunohistochemistry: 1:100-1:250 on frozen sections. Immunohistochemistry: 1:100-1:200. Immunoprecipitation: 1:100.
Presentation
No preservatives added
Storage
Aliquot and store at -20°C. Store undiluted for 6 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About BDNF
P23560 NM_001709 NP_001700.2

Validation

BDNF Antibody - Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)

BDNF Antibody - Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Mouse Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ BDNF Antibody for IHC, WB/Western, IP LS-B11849 has an LSBio Rating of
Laboratory Validation Score (5)

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Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/23/2022