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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BAIAP2 / IRSP53 Antibody (aa507‑518) LS‑C2961
Antibody
IRSP53 antibody LS-C2961 is an unconjugated rabbit polyclonal antibody to human IRSP53 (BAIAP2). Validated for ELISA.
Catalog
Size
Price
LS-C2961-100
100 µg
Unavailable

Popular BAIAP2 / IRSP53 Products

Anti-BAIAP2 / IRSP53 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2869 concentration 5 ug/ml.
Species: Human, Mouse, Rat, Dog, Pig
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Anti-BAIAP2 / IRSP53 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8289 dilution 3.75 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
BAIAP2 Antibody western blot of K562 cell line and mouse brain tissue lysates (35 ug/lane). The BAIAP2 antibody detected the BAIAP2 protein (arrow).
Species: Human, Mouse
Applications: Western blot
Immunohistochemical analysis of IRSp53 staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot

Product Description

IRSP53 antibody LS-C2961 is an unconjugated rabbit polyclonal antibody to human IRSP53 (BAIAP2). Validated for ELISA.
About BAIAP2 / IRSP53
BAIAP2 / IRSP53 has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Q9UQB8 NM_017450 NP_059344.1

BAIAP2 Antibody, BAI-associated protein 2 Antibody, BAI1-associated protein 2 Antibody, BAP2 Antibody, FLAF3 Antibody, Fas ligand-associated factor 3 Antibody, IRSP53 Antibody, IRS-58 Antibody, Protein BAP2 Antibody, Insulin receptor substrate p53 Antibody, IRSp53/58 Antibody


Specifications

Target
Human BAIAP2 / IRSP53
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA (1:1000)
Failed Applications
  • IHC - Paraffin
Immunogen
BAIAP2 / IRSP53 antibody was raised against synthetic peptide from human BAIAP2 / IRSP53. Percent identity by BLAST analysis: Human (100%); Gibbon, Mouse, Rat, Hamster (92%); Bovine (83%).
Epitope
aa507-518
Specificity
KLH conjugated synthetic peptide comprising amino acids 507 - 518 [ARSMSSADVEVA] of the human BAI1-associated protein 2 (BAIAP2) protein.
Presentation
PBS, 0.09% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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