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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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APAF1 / APAF‑1 Antibody (N‑Terminus) LS‑C51719
Antibody
APAF-1 antibody LS-C51719 is an unconjugated rabbit polyclonal antibody to human APAF-1 (APAF1). Validated for WB.
Catalog
Size
Price
LS-C51719-50
50 µg
Unavailable

Popular APAF1 / APAF-1 Products

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Anti-APAF1 / APAF-1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3340 concentration 10 ug/ml.
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Formalin-fixed, paraffin-embedded tissue sections of human brain tumors stained for Apaf 1 expression using LS-C148201 at 1:2000. A. Gemistocytoma (grade II). B. Anaplastic glioma. A high level of Apaf 1was observed in the gemistocytoma whereas a low level was seen in the more malignant anaplastic glioma. Hematoxylin-Eos in counterstain.
Species: Human, Mouse, Rat, Gerbil
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation, ELISA

Product Description

APAF-1 antibody LS-C51719 is an unconjugated rabbit polyclonal antibody to human APAF-1 (APAF1). Validated for WB.
About APAF1 / APAF-1
Apaf1 has been described as the core of the apoptosome. Deficiency in murine Apaf1 leads to embryonic lethality with a phenotype affecting many aspects of developmental apoptosis. In the developing brain, Apaf1 is a death regulator of the neuronal founder cells. Combined intercrosses of mouse lines mutant for members of the mitochondrial death pathway are providing us with some clues about the relative regulation existing among neuronal cell populations. O14727 NM_013229 NP_037361.1

APAF1 Antibody, APAF-1 Antibody, CED4 Antibody, KIAA0413 Antibody


Specifications

Target
Human APAF1 / APAF-1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
APAF1 / APAF-1 antibody was raised against peptide mapping to the amino terminus of human Apaf-1.
Epitope
N-Terminus
Specificity
Human Apaf-1
Presentation
PBS, 0.1% sodium azide, 0.2% gelatin.
Storage
4°C, avoid freezing.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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