Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone I2H5] (IgG1) to Human ACE / CD143
Human ACE / CD143
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [I2H5]
Specificity and Use
ACE / CD143 antibody was raised against human lung CD143 (Angiotensin converting enzyme).
Recognizes human CD143 and active ACE binding to an N-terminal domain epitope different to that recognized by clone 9B9.
Suitable for use in Flow cytometry: 10 ul labels of a neat-1:10 working dilution to 10^6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
0.09% sodium azide, 1.0% BSA
Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light.
ACE Antibody, ACE1 Antibody, Angiotensin-converting enzyme Antibody, CD143 Antibody, CD143 antigen Antibody, Carboxycathepsin Antibody, DIPEPTIDYL CARBOXYPEPTIDASE Antibody, DCP Antibody, Dipeptidyl carboxypeptidase I Antibody, ICH Antibody, Kininase II Antibody, MVCD3 Antibody, Peptidyl-dipeptidase A Antibody, Peptidase P Antibody, DCP1 Antibody, Dipeptidyl carboxypeptidase 1 Antibody, Testicular ECA Antibody
ACE / CD143 is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system.